The reactions of organic azides and alkynes catalysed by copper species represent the
prototypical examples of click chemistry. The so-called CuAAC reaction (copper-catalysed …

Highlights•Mutually orthogonal bioorthogonal reactions are described.•Current challenges
in compatible reaction development are outlined.•Strategies to identify and generate …

The copper (I)‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction regiospecifically
produces 1, 4‐disubstituted‐1, 2, 3‐triazole molecules. This heterocycle formation chemistry …

The concept of chelation‐assisted copper catalysis was employed for the development of
new azides that display unprecedented reactivity in the copper (I)‐catalyzed azide–alkyne …

We present an operationally simple iterative coupling strategy for the synthesis of oligomeric
homo-and hetero [n] rotaxanes with precise control over the position of each macrocycle …

Catalytic C− N bond formation by direct activation of C− H bonds offers wide synthetic
potential. En route to C− H amination, complexes with organic azides are critical precursors …

The Cu-catalyzed azide–alkyne cycloaddition (CuAAC) reaction is used as a ligation tool
throughout chemical and biological sciences. Despite the pervasiveness of CuAAC, there is …

Heterocyclic compounds with two to three nitrogen atoms play a pivotal role in the normal
life cycle of a cell. Further the design and synthesis of a quality heterocyclic compound …

The Cu-catalyzed azide–alkyne cycloaddition (CuAAC) reaction is a key ligation tool used to
prepare bioconjugates. Despite the widespread utility of CuAAC to produce discrete 1, 4 …

The Cu (I)-catalyzed azide-alkyne cycloaddition reaction, also known as click chemistry, has
become a useful tool for the facile formation of 1, 2, 3-triazoles. Specifically, the utility of this …