Cell death is an essential immunological apparatus of host defense, but dysregulation of
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …

Macrophages are immune cells with high plasticity that are widely distributed in all tissues
and organs of the body. Under the influence of the immune microenvironment of breast …

Natural killer (NK) cell protection from tumor metastases is a critical feature of the host
immune response to cancer, but various immunosuppression mechanisms limit NK cell …

Trichomonas vaginalis is a human infective parasite responsible for trichomoniasis–the most
common, non-viral, sexually transmitted infection worldwide. T. vaginalis resides exclusively …

Dysbiosis in the female genital tract (FGT) is characterized by the overgrowth of pathogenic
bacterial, fungal, or protozoan members of the microbiota, leading to symptomatic or …

Abstract Background Infection with Trichomonas vaginalis can lead to cervicitis, urethritis,
pelvic inflammatory disease, prostatitis and perinatal complications and increased risk of …

Trichomonas vaginalis is the pathological agent of human trichomoniasis. The incidence is
156 million cases worldwide. Due to the increasing resistance of isolates to approved drugs …

Disrupted mitochondrial function and reactive oxygen species (ROS) generation cause
cellular damage and oxidative stress‐induced macrophage inflammatory cell death. It …

Trichomoniasis is the third most common sexually transmitted infection in humans and is
caused by the protozoan parasite, Trichomonas vaginalis (Tv). Pathogenic outcomes are …

Body tissues are subjected to various oxygenic gradients and fluctuations and hence can
become transiently hypoxic. Hypoxia-inducible factor (HIF) is the master transcriptional …