Replicated international studies have underscored the human and societal costs associated
with major depressive disorder. Despite the proven efficacy of monoamine-based …

Ketamine produces immediate antidepressant effects and has inspired research into next-
generation treatments. Ketamine also has short term dissociative effects, in which …

Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

Therapeutic deficiencies with monoaminergic antidepressants invites the need to identify
and develop novel rapid-acting antidepressants. Hitherto, ketamine and esketamine are …

Objectif: Les patients souffrant de trouble dépressif majeur (TDM) ont souvent une réponse
limitée aux médicaments de première et de deuxième intention, donc de nouveaux …

Background Postpartum depression (PPD) is a common complication of cesarean section. S-
ketamine given intravenously during surgery can help prevent PPD. However, whether S …

Treatment resistant depression (TRD) is associated with poor outcomes, but a consensus is
lacking in the literature regarding which compound represents the best pharmacological …

Analysis of Nile flood stages from AD 640 to 1921 reveals major episodes of low Nile
discharge during the years 930 to 1070 and 1180 to 1350 and major episodes of high Nile …

The feasibility of intravenous ketamine administration during the perioperative period of
cesarean section to prevent postpartum depression (PPD) has not been determined by meta …

Background Ketamine is an effective short-term treatment for a range of psychiatric
disorders. A key question is whether the addition of psychotherapy to ketamine treatment …