Interactions between antidiabetic drugs and herbs: an overview of mechanisms of action and clinical implications

RC Gupta, D Chang, S Nammi, A Bensoussan… - Diabetology & metabolic …, 2017 - Springer
Diabetes is a complex condition with a variety of causes and pathophysiologies. The current
single target approach has not provided ideal clinical outcomes for the treatment of the …

Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature review

HH Tsai, HW Lin, A Simon Pickard… - … journal of clinical …, 2012 - Wiley Online Library
Summary Background and Aims: The use of herbs and dietary supplements (HDS) alone or
concomitantly with medications can potentially increase the risk of adverse events …

Very important pharmacogene summary

LM Hodges, SM Markova, LW Chinn… - Pharmacogenetics …, 2011 - journals.lww.com
ABCB1 (MDR1) is one of many ubiquitous adenosine triphosphate (ATP)-binding cassette
(ABC) genes present in all kingdoms of life that is responsible for cellular homeostasis [1–3] …

Herb-drug interactions and mechanistic and clinical considerations

XW Chen, KB Sneed, SY Pan, C Cao… - Current drug …, 2012 - ingentaconnect.com
Herbal medicines are often used in combination with conventional drugs, and this may give
rise to the potential of harmful herb-drug interactions. This paper updates our knowledge on …

Identification of drugs that interact with herbs in drug development

SF Zhou, ZW Zhou, CG Li, X Chen, X Yu, CC Xue… - Drug discovery today, 2007 - Elsevier
To date, several clinically important drugs have been identified that interact with commonly
used herbs. These drugs include (among others) warfarin, midazolam, digoxin, amitriptyline …

Clinical herbal interactions with conventional drugs: from molecules to maladies

XW Chen, ES Serag, KB Sneed… - Current medicinal …, 2011 - ingentaconnect.com
Clinical studies and case reports have identified a number of herb-drug interactions
potentiated by the concurrent use of herbal medicines with prescription drugs. The purpose …

Liver toxicity related to herbs and dietary supplements: Online table of case reports. Part 2 of 5 series

AC Brown - Food and Chemical Toxicology, 2017 - Elsevier
Background No online current list of potentially life-threatening, hepatotoxic herbs and
dietary supplements based on PubMed case reports exists in a summarized tabular form …

A review of potential harmful interactions between anticoagulant/antiplatelet agents and Chinese herbal medicines

HH Tsai, HW Lin, YH Lu, YL Chen, GB Mahady - PloS one, 2013 - journals.plos.org
Background The risks attributed to drug-herb interactions, even when known, are often
ignored or underestimated, especially for those involving anti-clotting drugs and Chinese …

Metabolic activation of herbal and dietary constituents and its clinical and toxicological implications: an update

SF Zhou, CC Xue, XQ Yu, G Wang - Current drug metabolism, 2007 - ingentaconnect.com
In recent years, there has been a globally increasing application of herbal medicines and
dietary supplements to treat various chronic diseases and to promote health. However, there …

Herbal bioactivation, molecular targets and the toxicity relevance

XW Chen, ES Serag, KB Sneed, SF Zhou - Chemico-biological interactions, 2011 - Elsevier
There have been increasing reports on the adverse reactions associated with herbal
consumption. For many of these adverse reactions, the underlying biochemical mechanisms …