CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and
mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is …

Posaconazole is a second-generation triazole agent with a potent and broad antifungal
activity. In addition to the oral suspension, a delayed-release tablet and intravenous …

Allogeneic hematopoietic cell transplantation (HCT) provides the best chance for cure for
many patients with malignant and nonmalignant hematologic disorders. Recent advances in …

Abstract As of 25th July, 2022, global Disease burden of 575,430,244 confirmed cases and
over 6,403,511 deaths have been attributed to coronavirus disease 2019 (COVID-19). Co …

Oral administration of drugs is preferred over other routes for several reasons: it is non-
invasive, easy to administer, and easy to store. However, drug formulation for oral …

Coronavirus disease 2019 (COVID-19) infection is currently a great cause of concern for the
healthcare sector around the globe. SARS-CoV-2 is an RNA virus that causes a serious …

Four model polymers, representing (i) amorphous homopolymers (Kollidon K30, K30),(ii)
amorphous heteropolymers (Kollidon VA64, KVA),(iii) semi-crystalline homopolymers …

Los azoles son fármacos que inhiben la enzima 14α-esteroldemetilasa, impidiendo la unión
de ergosterol; esto altera la estructura y función de la pared celular fúngica. Especialmente …

Introduction The current armamentarium of antifungal agents for invasive mold infections
(IMI) has dramatically improved over the last 50 years. Existing therapies are, however …

Invasive fungal wound infections (IFIs) were an unexpected complication associated with
blast-related wounds during Operation Enduring Freedom. Between 2010 and 2012, IFI …