Purpose: To update the ASCO guideline for antiemetics in oncology. Methods: ASCO
convened an Expert Panel and conducted a systematic review of the medical literature for …

Antiemetic Prophylaxis for Chemotherapy-Induced Nausea and Vomiting | NEJM Skip to main
content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to …

Despite the considerable progress achieved in the last 30 years, vomiting and, especially,
nausea, continue to be two of the most distressing side-effects of cancer chemotherapy. In …

Chemotherapy-induced nausea and vomiting (CINV) is associated with a significant
deterioration in quality of life and is perceived by patients as a major adverse effect of the …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Antiemesis
address all aspects of management for chemotherapy-induced nausea and vomiting. These …

An unprecedented enantioselective synthesis of spiro‐γ‐lactams via a sequential C− H
olefination/asymmetric [4+ 1] spirocyclization under a simple CoII/chiral spiro phosphoric …

Background Highly emetogenic chemotherapy induces emesis in almost all patients in the
absence of prophylaxis. Guidelines recommend use of a neurokinin-1 (NK-1) receptor …

Purpose This review summarizes the recommendations for the prophylaxis of nausea and
vomiting in adults receiving highly emetogenic chemotherapy (HEC) which includes …

Even when chemotherapy-induced nausea and vomiting (CINV) can be effectively
controlled in the acute phase, it may still occur in the delayed phase. Identifying at-risk …

While progress in enantioselective C–H functionalization has been accomplished by
employing 4d and 5d transition metal-based catalysts, the rapid depletion of these metals in …