Duchenne muscular dystrophy (DMD) is a monogenic muscle-wasting disorder and a
priority candidate for molecular and cellular therapeutics. Although rare, it is the most …

Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disorder. It is caused
by loss-of-function mutations in the dystrophin gene. Currently, there is no cure. A highly …

Duchenne muscular dystrophy (DMD) is an X-linked recessive, infancy-onset
neuromuscular disorder characterized by progressive muscle weakness and atrophy …

Muscular dystrophy (MD) is a group of progressive genetic diseases affecting the
musculature that are characterized by inflammatory infiltrates, necrosis and connective …

Research into fundamental principles and the testing of therapeutic hypotheses for treatment
of human disease is commonly performed on mouse models of human diseases. Although …

Duchenne muscular dystrophy is a progressive and incurable neuromuscular disease
caused by genetic and biochemical defects of the dystrophin–glycoprotein complex. Here …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy.
There is no effective treatment and patients typically die in approximately the third decade …

Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder caused by
mutations in the dystrophin gene that result in the absence of functional protein. Antisense …

The essential product of the Duchenne muscular dystrophy (DMD) gene is dystrophin, a rod-
like protein that protects striated myocytes from contraction-induced injury,. Dystrophin …

Gene mutations causing loss of dystrophin result in the severe muscle disease known as
Duchenne muscular dystrophy (DMD). Despite efforts at genetic repair, DMD therapy …