Measuring mechanical stress in living tissues
Living tissues are active, multifunctional materials capable of generating, sensing,
withstanding and responding to mechanical stress. These capabilities enable tissues to …
withstanding and responding to mechanical stress. These capabilities enable tissues to …
[HTML][HTML] The excitable signal transduction networks: movers and shapers of eukaryotic cell migration
In response to a variety of external cues, eukaryotic cells display varied migratory modes to
perform their physiological functions during development and in the adult. Aberrations in cell …
perform their physiological functions during development and in the adult. Aberrations in cell …
Three-dimensional balance of cortical tension and axial contractility enables fast amoeboid migration
B Álvarez-González, R Meili, E Bastounis, RA Firtel… - Biophysical journal, 2015 - cell.com
Fast amoeboid migration requires cells to apply mechanical forces on their surroundings via
transient adhesions. However, the role these forces play in controlling cell migration speed …
transient adhesions. However, the role these forces play in controlling cell migration speed …
Cancer Metastasis‐on‐a‐Chip for Modeling Metastatic Cascade and Drug Screening
A Brooks, Y Zhang, J Chen… - Advanced Healthcare …, 2024 - Wiley Online Library
Microfluidic chips are valuable tools for studying intricate cellular and cell–microenvironment
interactions. Traditional in vitro cancer models lack accuracy in mimicking the complexities …
interactions. Traditional in vitro cancer models lack accuracy in mimicking the complexities …
Coupling traction force patterns and actomyosin wave dynamics reveals mechanics of cell motion
Motile cells can use and switch between different modes of migration. Here, we use traction
force microscopy and fluorescent labeling of actin and myosin to quantify and correlate …
force microscopy and fluorescent labeling of actin and myosin to quantify and correlate …
Self-organized mechano-chemical dynamics in amoeboid locomotion of Physarum fragments
The aim of this work is to quantify the spatio-temporal dynamics of flow-driven amoeboid
locomotion in small (∼ 100 μm) fragments of the true slime mold Physarum polycephalum …
locomotion in small (∼ 100 μm) fragments of the true slime mold Physarum polycephalum …
Two-layer elastographic 3-D traction force microscopy
B Álvarez-González, S Zhang, M Gómez-González… - Scientific Reports, 2017 - nature.com
Cellular traction force microscopy (TFM) requires knowledge of the mechanical properties of
the substratum where the cells adhere to calculate cell-generated forces from …
the substratum where the cells adhere to calculate cell-generated forces from …
Dendritic cell force-migration coupling on aligned fiber networks
C Hernandez-Padilla, B Joosten, A Franco, A Cambi… - Biophysical …, 2024 - cell.com
Dendritic cells (DCs) are antigen-presenting cells that reside in peripheral tissues and are
responsible for initiating adaptive immune responses. As gatekeepers of the immune …
responsible for initiating adaptive immune responses. As gatekeepers of the immune …
Formation of multicellular colonies by choanoflagellates increases susceptibility to capture by amoeboid predators
NE Chin, TC Wu, JM O'Toole, K Xu… - Journal of Eukaryotic …, 2023 - Wiley Online Library
Many heterotrophic microbial eukaryotes are size‐selective feeders. Some microorganisms
increase their size by forming multicellular colonies. We used choanoflagellates …
increase their size by forming multicellular colonies. We used choanoflagellates …
Traditional Plant-Derived Compounds Inhibit Cell Migration and Induce Novel Cytoskeletal Effects in Glioblastoma Cells
E Thompson, S Prior, A Brüning-Richardson - Journal of Xenobiotics, 2024 - mdpi.com
Glioblastomas (GBMs) are aggressive and invasive cancers of the brain, associated with
high rates of tumour recurrence and poor patient outcomes despite initial treatment …
high rates of tumour recurrence and poor patient outcomes despite initial treatment …