Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Advances in the biological studies of metal-terpyridine complexes: an overview from 2012 to 2022

R Abhijnakrishna, K Magesh, A Ayushi… - Coordination Chemistry …, 2023 - Elsevier
Abstract The compound 2, 2′; 6, 2 ″terpyridine has attracted significant interest in the
fields of supramolecular chemistry, materials science, and coordination chemistry due to its …

Synthesis, characterization, crystal structure, DNA and HSA Interactions, and anticancer activity of a mononuclear Cu (II) complex with a Schiff base ligand containing …

SU Parsekar, K Paliwal, P Haldar, PKS Antharjanam… - ACS …, 2022 - ACS Publications
A mononuclear Cu (II) complex [Cu (HL)(o-phen)]· H2O (1)[H3L=, o-phen= 1, 10-
phenanthroline] was isolated from methanol, and its X-ray single-crystal structure was …

Cytotoxicity and mechanism of action of metal complexes: An overview

S Abdolmaleki, S Khaksar, A Aliabadi, A Panjehpour… - Toxicology, 2023 - Elsevier
After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …

Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands

LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …

Synthesis, DNA binding, antibacterial and anticancer properties of two novel water-soluble copper (II) complexes containing gluconate

DH Cai, CL Zhang, QY Liu, L He, YJ Liu… - European Journal of …, 2021 - Elsevier
In this paper, two new Cu (II) complexes,[Cu (Gluc)(HPB)(H 2 O)] Gluc (CuG1) and [Cu
(Gluc)(HPBC)(H 2 O)] Gluc (CuG2)(where HPB= 2-(2′-pyridyl) benzimidazole, HPBC= 5 …

Studies on the influence of the nuclearity of zinc (ii) hemi-salen complexes on some pivotal biological applications

BK Kundu, SM Mobin, S Mukhopadhyay - Dalton Transactions, 2020 - pubs.rsc.org
Though a large amount of literature has been reported on outlining the biological
significance of zinc (II) Schiff base complexes, yet none of them have explored the influence …

Targeting of DNA molecules, BSA/c-Met tyrosine kinase receptors and anti-proliferative activity of bis (terpyridine) copper (II) complexes

D Mahendiran, RS Kumar, V Viswanathan… - Dalton …, 2016 - pubs.rsc.org
A series of homoleptic bis (terpyridine) copper (II) complexes of the type [Cu (L1–5) 2] Cl2 (1–
5), where L1–5= 4′-(4-substituted)-2, 2′: 6′, 2′′-terpyridines, have been synthesized …

Protein binding studies with human serum albumin, molecular docking and in vitro cytotoxicity studies using HeLa cervical carcinoma cells of Cu (II)/Zn (II) complexes …

SU Parsekar, P Velankanni, S Sridhar, P Haldar… - Dalton …, 2020 - pubs.rsc.org
The interaction of two binuclear mixed ligand Cu (II) complexes [Cu (o-phen) LCu (OAc)](1)
and [Cu (o-phen) LCu (o-phen)](OAc)(2)(H3L= o-HOC6H4C (H) N–NH–C (OH) N–NC (H) …

Terpyridines as promising antitumor agents: An overview of their discovery and development

R Musiol, P Malecki, M Pacholczyk… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction The fused aromatic system of terpyridines makes them good, innocent ligands
for various metals. The resulting complexes have been extensively studied for both their …