[HTML][HTML] Role and clinical significance of TGF‑β1 and TGF‑βR1 in malignant tumors

J Wang, H Xiang, Y Lu, T Wu - … journal of molecular …, 2021 - spandidos-publications.com
The appearance and growth of malignant tumors is a complicated process that is regulated
by a number of genes. In recent years, studies have revealed that the transforming growth …

[HTML][HTML] Recent development in biomedical applications of oligonucleotides with triplex-forming ability

I Bekkouche, AY Shishonin, AA Vetcher - Polymers, 2023 - mdpi.com
A DNA structure, known as triple-stranded DNA, is made up of three oligonucleotide chains
that wind around one another to form a triple helix (TFO). Hoogsteen base pairing describes …

[HTML][HTML] Aberrant hypermethylation-mediated downregulation of antisense lncRNA ZNF667-AS1 and its sense gene ZNF667 correlate with progression and prognosis …

Z Dong, S Li, X Wu, Y Niu, X Liang, L Yang, Y Guo… - Cell Death & …, 2019 - nature.com
Natural antisense lncRNAs can interfere with their corresponding sense transcript to elicit
concordant or discordant regulation. LncRNA ZNF667-AS1 and its sense gene ZNF667 …

[HTML][HTML] Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma

W Meng, W Cui, L Zhao, W Chi, H Cao… - Journal of Biomedical …, 2019 - Springer
Abstract Background Dysregulated long noncoding RNAs (lncRNAs) are involved in the
development of tumor. Aberrant methylation is one of the most frequent epigenetic …

A universal model of RNA. DNA: DNA triplex formation accurately predicts genome-wide RNA–DNA interactions

T Warwick, S Seredinski, NM Krause… - Briefings in …, 2022 - academic.oup.com
Abstract RNA. DNA: DNA triple helix (triplex) formation is a form of RNA–DNA interaction
which regulates gene expression but is difficult to study experimentally in vivo. This makes …

Long non‐coding RNA expression profile associated with malignant progression of oral submucous fibrosis

S Zhou, Y Zhu, Z He, D Zhang, F Guo, X Jian… - Journal of …, 2019 - Wiley Online Library
Oral submucous fibrosis (OSF) as one of the premalignant disorders endures a series of
histopathological stages to invasive oral squamous cell carcinoma (OSCC) eventually …

Expression profile of lncRNAs and miRNAs in esophageal cancer: Implications in diagnosis, prognosis, and therapeutic response

S Ghafouri‐Fard, H Shoorei, S Dashti… - Journal of Cellular …, 2020 - Wiley Online Library
Esophageal cancer is the seventh most common cancer worldwide. Although a number of
environmental and lifestyle‐related risk factors have been identified for this kind of cancer …

[HTML][HTML] Non-coding RNAs as biomarkers of tumor progression and metastatic spread in epithelial ovarian cancer

K Seborova, R Vaclavikova, L Rob, P Soucek… - Cancers, 2021 - mdpi.com
Simple Summary Despite advances in cancer research in recent years, efficient predictive
biomarkers of tumor progression and metastatic spread for ovarian cancer are still missing …

[HTML][HTML] DNA methylation as a diagnostic biomarker for malignant mesothelioma: a systematic review and meta-analysis

J Vandenhoeck, JP van Meerbeeck, E Fransen… - Journal of Thoracic …, 2021 - Elsevier
Malignant mesothelioma is an aggressive cancer type linked to asbestos exposure.
Because of several intrinsic challenges, mesothelioma is often diagnosed in an advanced …

ZNF667‐AS1, a positively regulating MEGF10, inhibits the progression of uveal melanoma by modulating cellular aggressiveness

H Yang, MY Cai, H Rong, LR Ma… - Journal of Biochemical …, 2021 - Wiley Online Library
Zinc finger protein 667‐antisense RNA 1 (ZNF667‐AS1) is a member of the C2H2 zinc
finger protein family. However, the exact effect of ZNF667‐AS1 in uveal melanoma (UM) …