Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …
research. Several drugs currently used as therapeutic agents have been developed from …
Review on natural products databases: where to find data in 2020
M Sorokina, C Steinbeck - Journal of cheminformatics, 2020 - Springer
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …
last decencies and the interest around them continues to grow incessantly. As a …
Natural product drug discovery in the artificial intelligence era
FI Saldívar-González, VD Aldas-Bulos… - Chemical …, 2022 - pubs.rsc.org
Natural products (NPs) are primarily recognized as privileged structures to interact with
protein drug targets. Their unique characteristics and structural diversity continue to marvel …
protein drug targets. Their unique characteristics and structural diversity continue to marvel …
Natural product-based nanoformulations for cancer therapy: Opportunities and challenges
Application of natural product-based nanoformulations for the treatment of different human
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …
Counting on natural products for drug design
Natural products and their molecular frameworks have a long tradition as valuable starting
points for medicinal chemistry and drug discovery. Recently, there has been a revitalization …
points for medicinal chemistry and drug discovery. Recently, there has been a revitalization …
The re-emergence of natural products for drug discovery in the genomics era
AL Harvey, RA Edrada-Ebel, RJ Quinn - Nature reviews drug discovery, 2015 - nature.com
Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …
use has diminished in the past two decades, in part because of technical barriers to …
Unraveling plant natural chemical diversity for drug discovery purposes
E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …
benefit from the immense natural chemical diversity is a concern in many laboratories …
Natural products as a source for novel antibiotics
MG Moloney - Trends in pharmacological sciences, 2016 - cell.com
Natural products have historically been of crucial importance in the identification and
development of antibacterial agents. Interest in these systems has waned in recent years …
development of antibacterial agents. Interest in these systems has waned in recent years …
Natural products in drug discovery
AL Harvey - Drug discovery today, 2008 - Elsevier
Natural products have been the single most productive source of leads for the development
of drugs. Over a 100 new products are in clinical development, particularly as anti-cancer …
of drugs. Over a 100 new products are in clinical development, particularly as anti-cancer …
Natural products in crop protection
The tremendous increase in crop yields associated with the 'green'revolution has been
possible in part by the discovery and utilization of chemicals for pest control. However …
possible in part by the discovery and utilization of chemicals for pest control. However …