The circadian clock is a regulatory system, with a periodicity of approximately 24 h, that
generates rhythmic changes in many physiological processes. Increasing evidence links …

Aging is the most important factor contributing to cardiovascular diseases (CVDs), and the
incidence and severity of cardiovascular events tend to increase with age. Currently, CVD is …

Background Ischemic niche can promote follicular atresia following the transplantation of
cryopreserved/thawed ovaries to the heterotopic sites. Thus, the promotion of blood supply …

Melatonin, the 'hormone of darkness' is a neuronal hormone secreted by the pineal gland
and other extra pineal sites. Responsible for the circadian rhythm and seasonal behaviour of …

Endothelial cells are constantly exposed to environmental stress factors that, above a certain
threshold, trigger cellular senescence and apoptosis. The altered vascular function affects …

Cardiovascular diseases (CVDs) are the leading causes of death and illness worldwide.
While there have been advancements in the treatment of CVDs using medication and …

Background Complexity and heterogeneity of the tumor niche are closely associated with
the failure of therapeutic protocols. Unfortunately, most data have been obtained from …

Ischemic stroke is a major public health problem worldwide. Although the circadian clock is
involved in the process of ischemic stroke, the exact mechanism of the circadian clock in …

Dynamic brain activity requires timely communications between the brain parenchyma and
circulating blood. Brain–blood communication is facilitated by intricate networks of brain …

Bisphenol A (BPA), an endocrine disruptor, changes many physiological functions of the
body, especially the reproductive system. The malfunction of the reproductive system after …