Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

Simple Summary The genomics-based concept of precision medicine began to emerge
following the completion of the Human Genome Project. In contrast to evidence-based …

Cancer, a complex yet common disease, is caused by uncontrolled cell division and
abnormal cell growth due to a variety of gene mutations. Seeking effective treatments for …

Drug discovery is important in cancer therapy and precision medicines. Traditional
approaches of drug discovery are mainly based on in vivo animal experiments and in vitro …

Precision medicine is the new age medicine and refers to tailoring treatments to a
subpopulation who have a common susceptibility to a particular disease or similar response …

Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

Deep generative models for molecular generation have been gaining much attention as
structure generators to accelerate drug discovery. However, most previously developed …

While conventional cancer treatments, such as surgery, radiotherapy and chemotherapy,
have been combined for decades in an effort to treat cancer patients, the emergence of …

Background Network medicine is an emerging area of research that focuses on delving into
the molecular complexity of the disease, leading to the discovery of network biomarkers and …

Deciphering the variations in the protein interactome is required to reach a systems-level
understanding of tumorigenesis. To accomplish this task, we have considered the clinical …