MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

Aging is a major risk factor for most chronic diseases and functional impairments. Within a
homogeneous age sample there is a considerable variation in the extent of disease and …

The central nervous system can respond to threat via the induction of an inflammatory
response. Under normal circumstances this response is tightly controlled, however …

Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …

Background Minimally invasive specific biomarkers of neurodegenerative diseases (NDs)
would facilitate patient selection and disease progression monitoring. We describe the …

Neurodegenerative diseases (NDs) are age-dependent; among them, Alzheimer's disease
(AD) and Parkinson's disease (PD) are the most frequent. Similarly, cerebrovascular …

MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

Nucleic acid drugs have the advantages of rich target selection, simple in design, good and
enduring effect. They have been demonstrated to have irreplaceable superiority in brain …

Neurodegeneration is a highly complex process which is associated with a variety of
molecular mechanisms related to ageing. Among neurodegenerative disorders, Alzheimer's …

Diabetes mellitus (DM) is a common disease worldwide. There is a strong association
between DM and neurovascular and neurodegenerative disorders. The first group mainly …