The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Natural biomacromolecules have attracted increased attention as carriers in biomedicine in
recent years because of their inherent biochemical and biophysical properties including …

Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

BACKGROUND: Traditional cancer therapy can be successful in destroying tumors, but can
also cause dangerous side effects. Therefore, many targeted therapies are in development …

Gene transfer methods are promising in the field of gene therapy. Current methods for gene
transfer include three major groups: viral, physical and chemical methods. This review …

Injectable nanoparticulate carriers have important potential applications such as site-specific
drug delivery or medical imaging. Conventional carriers, however, cannot generally be used …

Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

In the chitin bibliography, a major reference is the book written by Richards in 1951
“primarily for entomologists and other invertebrate zoologists” but also, in the author's hope …

The lack of safe and efficient gene-delivery methods is a limiting obstacle to human gene
therapy. Synthetic gene-delivery agents, although safer than recombinant viruses, generally …

The folate receptor is a highly selective tumor marker overexpressed in greater than 90% of
ovarian carcinomas. Two general strategies have been developed for the targeted delivery …