In chronic lymphocytic leukemia (CLL), analysis of TP53 aberrations (deletion and/or
mutation) is a crucial part of treatment decision-making algorithms. Technological and …

Simple Summary Next–Generation Sequencing (NGS) has provided a deeper genetic
understanding of acute myeloid leukemia (AML) that has been recently incorporated into …

Introduction: Acute lymphoblastic leukemia (ALL) is a prevalent childhood cancer with high
cure rate, but poses a significant medical challenge in adults and relapsed patients …

The molecular landscape of acute lymphoblastic leukemia (ALL) is highly heterogeneous,
and genetic lesions are clinically relevant for diagnosis, risk stratification, and treatment …

TP53 aberrations predict chemoresistance and represent a contraindication for the use of
standard chemoimmunotherapy in chronic lymphocytic leukaemia (CLL). Recent next …

TP53 aberrations are a major predictive factor of resistance to chemoimmunotherapy in
chronic lymphocytic leukemia (CLL), and an assessment of them before each line of …

In a recent issue of HemaSphere, Pandzic and colleagues 1 provide evidence that the use
of next generation sequencing (NGS) in chronic lymphocytic leukemia (CLL) clinical practice …

Motivation: Somatic variant calling algorithms are widely used to detect genomic alterations
associated with cancer. Evaluating their performance, even though being crucial, can be …

Περίληψη Η Χρόνια Λεμφοκυτταρική Λευχαιμία (ΧΛΛ) είναι η πιο κοινή μορφή λευχαιμίας
στον Δυτικό κόσμο και χαρακτηρίζεται από μεγάλη κλινική ετερογένεια η οποία σχετίζεται με …