Chronic obstructive pulmonary disease (COPD) represents a worldwide concern with high
morbidity and mortality, and is believed to be associated with accelerated ageing of the lung …

Background CXCR4, a transmembrane-receptor located on epithelial cells that is activated
by CXCL12, may have a role in IPF via migration of CXCR4+ fibrocytes to the lung …

In addition to their modulation through de novo expression and degradation, surface levels
of chemokine receptors are tuned by their ligand-dependent recycling to the plasma …

Bronchopulmonary dysplasia (BPD) is the most common challenge in preterm neonates.
Retardation of alveolar development characterizes the pulmonary pathology in BPD. In the …

Proliferation and migration of lung epithelial cells following the injury to the epithelial lining
of alveoli and airways in the lung are pivotal for remodeling and repair of the wound to …

Mechanical ventilation induces lung injury by damaging alveolar epithelial cells (AECs), but
the pathogenesis remains unknown. Focal adhesion kinase (FAK) is a cytoplasmic protein …

Abstract Angiotensin converting enzyme 2 (ACE2) is an enzyme that limits activity of the
renin-angiotensin system (RAS) and also serves as a receptor for the SARS-CoV-2 Spike …

i TITLE PAGE Role of ASK1 in Platelet Activation and ImmuneГInduced Throm@ocytopenia and
Throm@osis. Pravin Patel, BA A Disse Page 1 i TITLE PAGE Role of ASK1 in Platelet Activation …

Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow
limitation and represents a public health problem worldwide. Defective epithelial repair is a …

Epithelial cell lining of the lung alveoli is under constant onslaught of airborne pathogens
and pollutants that may cause injury and disruption of the epithelial lining. Repair …