Quantum Dot–Peptide–Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential
OK Nag, MH Stewart, JR Deschamps, K Susumu… - ACS …, 2017 - ACS Publications
We report the development of a quantum dot (QD)–peptide–fullerene (C60) electron transfer
(ET)-based nanobioconjugate for the visualization of membrane potential in living cells. The …
(ET)-based nanobioconjugate for the visualization of membrane potential in living cells. The …
Design and demonstration of an intracortical probe technology with tunable modulus
DM Simon, H Charkhkar, C St. John… - … Research Part A, 2017 - Wiley Online Library
Intracortical probe technology, consisting of arrays of microelectrodes, offers a means of
recording the bioelectrical activity from neural tissue. A major limitation of existing …
recording the bioelectrical activity from neural tissue. A major limitation of existing …
Improving the performance of poly (3, 4-ethylenedioxythiophene) for brain–machine interface applications
HS Mandal, GL Knaack, H Charkhkar, DG McHail… - Acta biomaterialia, 2014 - Elsevier
Abstract Conducting polymers, especially poly (3, 4-ethylenedioxythiophene)(PEDOT)
based materials, are important for developing highly sensitive and microscale neural …
based materials, are important for developing highly sensitive and microscale neural …
Amyloid beta modulation of neuronal network activity in vitro
H Charkhkar, S Meyyappan, E Matveeva, JR Moll… - Brain research, 2015 - Elsevier
In vitro assays offer a means of screening potential therapeutics and accelerating the drug
development process. Here, we utilized neuronal cultures on planar microelectrode arrays …
development process. Here, we utilized neuronal cultures on planar microelectrode arrays …
Use of cortical neuronal networks for in vitro material biocompatibility testing
Neural interfaces aim to restore neurological function lost during disease or injury. Novel
implantable neural interfaces increasingly capitalize on novel materials to achieve …
implantable neural interfaces increasingly capitalize on novel materials to achieve …
Establishment of a human neuronal network assessment system by using a human neuron/astrocyte co-culture derived from fetal neural stem/progenitor cells
K Fukushima, Y Miura, K Sawada… - Journal of …, 2016 - journals.sagepub.com
Using human cell models mimicking the central nervous system (CNS) provides a better
understanding of the human CNS, and it is a key strategy to improve success rates in CNS …
understanding of the human CNS, and it is a key strategy to improve success rates in CNS …
A Framework for the Comparative Assessment of Neuronal Spike Sorting Algorithms towards More Accurate Off‐Line and On‐Line Microelectrode Arrays Data …
Neuronal spike sorting algorithms are designed to retrieve neuronal network activity on a
single‐cell level from extracellular multiunit recordings with Microelectrode Arrays (MEAs). In …
single‐cell level from extracellular multiunit recordings with Microelectrode Arrays (MEAs). In …
Amorphous silicon carbide for neural interface applications
GL Knaack, H Charkhkar, SF Cogan… - Silicon Carbide …, 2016 - Elsevier
Implantable neural interfaces offer promise as prosthetic devices that enable communication
and control of artificial limbs for individuals suffering from paralysis and amputation. While …
and control of artificial limbs for individuals suffering from paralysis and amputation. While …
Novel disposable microelectrode array for cultured neuronal network recording exhibiting equivalent performance to commercially available arrays
Microelectrode arrays (MEAs) enable non-invasive recording of supra-threshold signals, ie
action potentials or spikes, from a variety of cultured electrically active cells. While this label …
action potentials or spikes, from a variety of cultured electrically active cells. While this label …
Time-dependent increase in network response to stimulation
In vitro neuronal cultures have become a popular method with which to probe network-level
neuronal dynamics and phenomena in controlled laboratory settings. One of the key …
neuronal dynamics and phenomena in controlled laboratory settings. One of the key …