Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …

It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Purpose: Testis cancer is the most common solid malignancy in young males. The purpose
of this guideline is to provide a useful reference on the effective evidence-based treatment of …

Non-epithelial ovarian cancers (NEOC) are a group of uncommon malignancies that mainly
includes germ cell tumours (GCT), sex cord-stromal tumours (SCST), and some extremely …

Controversy surrounds reports describing the derivation of human trophoblast cells from
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …

Context Clinical management of testicular germ cell tumours (GCTs) is hampered by low
sensitivity and specificity of the biomarkers currently in use. Circulating microRNAs (miRs) …

Background Clinical management of germ cell tumours (GCTs) relies on monitoring of
serum tumour markers. However, the markers α-fetoprotein (AFP), the β-subunit of human …

The management of intracranial germ-cell tumours is complex because of varied clinical
presentations, tumour sites, treatments and outcomes, and the need for multidisciplinary …

Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …

MicroRNAs (miRNAs) are expressed in the placenta and can be detected in maternal
plasma. An increasing number of studies have been published on the cellular origin …