Assembly of bacterial capsular polysaccharides and exopolysaccharides

C Whitfield, SS Wear, C Sande - Annual Review of Microbiology, 2020 - annualreviews.org
Polysaccharides are dominant features of most bacterial surfaces and are displayed in
different formats. Many bacteria produce abundant long-chain capsular polysaccharides …

Structure and genetics of Escherichia coli O antigens

B Liu, A Furevi, AV Perepelov, X Guo… - FEMS microbiology …, 2020 - academic.oup.com
Escherichia coli includes clonal groups of both commensal and pathogenic strains, with
some of the latter causing serious infectious diseases. O antigen variation is current …

Assembly and maintenance of lipids at the bacterial outer membrane

E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …

Lipopolysaccharide O-antigens—bacterial glycans made to measure

C Whitfield, DM Williams, SD Kelly - Journal of Biological Chemistry, 2020 - ASBMB
Lipopolysaccharides are critical components of bacterial outer membranes. The more
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …

Microbial glycoconjugates in organic pollutant bioremediation: recent advances and applications

P Bhatt, A Verma, S Gangola, G Bhandari, S Chen - Microbial cell factories, 2021 - Springer
The large-scale application of organic pollutants (OPs) has contaminated the air, soil, and
water. Persistent OPs enter the food supply chain and create several hazardous effects on …

Architecture of a channel-forming O-antigen polysaccharide ABC transporter

Y Bi, E Mann, C Whitfield, J Zimmer - Nature, 2018 - nature.com
O-antigens are cell surface polysaccharides of many Gram-negative pathogens that aid in
escaping innate immune responses. A widespread O-antigen biosynthesis mechanism …

Targeting the Sugary Armor of Klebsiella Species

LPP Patro, T Rathinavelan - Frontiers in cellular and infection …, 2019 - frontiersin.org
The emergence of multidrug-resistant strains of Gram-negative Klebsiella species is an
urgent global threat. The World Health Organization has listed Klebsiella pneumoniae as …

Biosurfactant: a next-generation tool for sustainable remediation of organic pollutants

N Sharma, M Lavania, B Lal - Frontiers in Microbiology, 2022 - frontiersin.org
Petroleum hydrocarbons are energy resources that majorly contribute pollutants to the
environment. These pollutants may cause serious health issues, and hence, for the …

Microbial synthesis of glycosaminoglycans and their oligosaccharides

K Liu, L Guo, X Chen, L Liu, C Gao - Trends in Microbiology, 2023 - cell.com
Compared with chemical synthesis and tissue extraction methods, microbial synthesis of
glycosaminoglycans (GAGs) is attractive because of the advantages of eco-friendly …

Diverse mechanisms of polysaccharide biosynthesis, assembly and secretion across kingdoms

Z Stephens, LFL Wilson, J Zimmer - Current Opinion in Structural Biology, 2023 - Elsevier
Polysaccharides are essential biopolymers produced in all kingdoms of life. On the cell
surface, they represent versatile architectural components, forming protective capsules and …