[HTML][HTML] Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation

J Krstić, S Mojsilović, SS Mojsilović… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Bone regeneration is a tightly regulated process that ensures proper repair and functionality
after injury. The delicate balance between bone formation and resorption is governed by …

Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6

M Purwaningrum, CM Giachelli, T Osathanon… - Scientific Reports, 2023 - nature.com
Periodontal ligament stem cells (PDLSCs) play a significant role on periodontal tissue and
alveolar bone homeostasis. During inflammation, interleukin (IL)-6 serves as one of key …

Calcination and ion substitution improve physicochemical and biological properties of nanohydroxyapatite for bone tissue engineering applications

A Kurzyk, A Szwed-Georgiou, J Pagacz, A Antosik… - Scientific Reports, 2023 - nature.com
Nanohydroxyapatite (nanoHAP) is widely used in bone regeneration, but there is a need to
enhance its properties to provide stimuli for cell commitment and osteoconduction. This …

Effect of morphological characteristics and biomineralization of 3D-printed gelatin/hyaluronic acid/hydroxyapatite composite scaffolds on bone tissue regeneration

JW Kim, YS Han, HM Lee, JK Kim, YJ Kim - International journal of …, 2021 - mdpi.com
The use of porous three-dimensional (3D) composite scaffolds has attracted great attention
in bone tissue engineering applications because they closely simulate the major features of …

IL-17 promotes osteoblast differentiation, bone regeneration, and remodeling in mice

HJ Kim, SJ Seo, JY Kim, YG Kim, Y Lee - Biochemical and Biophysical …, 2020 - Elsevier
Bone homeostasis is maintained by concerted actions of bone-forming osteoblasts and
bone-resorbing osteoclasts. A wide range of evidence indicates that a proinflammatory …

[HTML][HTML] Phosvitin phosphopeptides produced by pressurized hea-trypsin hydrolysis promote the differentiation and mineralization of MC3T3-E1 cells via the OPG …

M Zhao, S Li, DU Ahn, X Huang - Poultry science, 2021 - Elsevier
Phosvitin (PV) from egg yolk is an excellent substrate for the production of phosphopeptides,
which have a strong calcium chelating capacity and promoting calcium absorption and bone …

Electrospun artificial periosteum loaded with DFO contributes to osteogenesis via the TGF-β1/Smad2 pathway

R Shi, J Zhang, K Niu, W Li, N Jiang, J Li, Q Yu… - Biomaterials …, 2021 - pubs.rsc.org
Deferoxamine (DFO), an iron chelator regarded as a hypoxic analogue, has been reported
to be involved in angiogenesis and osteogenic differentiation. In this study, DFO was loaded …

Probing the interaction between metastatic breast cancer cells and osteoblasts in a thread-based breast–bone co-culture device

SM Wu, F Chen, XY Yang, TF Wu, W Sun, L Yu - Lab on a Chip, 2023 - pubs.rsc.org
Breast cancer metastasis to bone is a leading killer in breast cancer patients. A type I
collagen-modified thread (Col-I@ thread) was prepared for 3-dimensional cell culture and …

Bilayered porous composite scaffolds for enhanced treatment of bone cancer through chemo-photothermal combination therapy

JW Kim, JH Kwon, KH Kim, YJ Kim - Macromolecular Research, 2024 - Springer
The combination of therapeutic materials and biocompatible scaffolds to create
multifunctional scaffolds with therapeutic and restorative functions has been investigated as …

Interleukin-17A promotes proliferation and osteogenic differentiation of human ligamentum flavum cells through regulation of β-catenin signaling

J Lin, S Jiang, Q Xiang, Y Zhao, L Wang, D Fan… - Spine, 2023 - journals.lww.com
Study Design. A basic experimental study. Objective. To elucidate the role and mechanism
of interleukin (IL)-17A in thoracic ossification of the ligamentum flavum (TOLF). Summary of …