Regulatory mechanism of miR-20a-5p expression in Cancer

W Huang, X Wu, S Xiang, M Qiao, X Cen, X Pan… - Cell Death …, 2022 - nature.com
MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules encoded by
endogenous genes with a length of about 22 nucleotides. The dysregulation of miRNAs has …

[HTML][HTML] Emerging roles of CircRNA-miRNA networks in cancer development and therapeutic response

M Hashemi, EM Khosroshahi, P Daneii… - Non-coding RNA …, 2024 - Elsevier
The complex interplay of epigenetic factors is essential in regulating the hallmarks of cancer
and orchestrating intricate molecular interactions during tumor progression. Circular RNAs …

CAF-released exosomal miR-20a-5p facilitates HCC progression via the LIMA1-mediated β-catenin pathway

Y Qi, H Wang, Q Zhang, Z Liu, T Wang, Z Wu, W Wu - Cells, 2022 - mdpi.com
Currently, exosomes derived from Cancer-associated fibroblast (CAF) have reportedly been
involved in regulating hepatocellular carcinoma (HCC) tumour microenvironment (TME). LIM …

Prediction of circRNA-miRNA association using singular value decomposition and graph neural networks

Y Qian, J Zheng, Y Jiang, S Li… - IEEE/ACM Transactions …, 2022 - ieeexplore.ieee.org
A large number of experimental studies have shown that circRNAs can act as molecular
sponges of microRNAs, interacting with miRNAs to regulate gene expression levels, thereby …

Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of …

E Heydarnia, Z Dorostgou, N Hedayati… - Cell Communication and …, 2024 - Springer
Cervical cancer (CC) is a common gynecologic malignancy, accounting for a significant
proportion of women death worldwide. Human papillomavirus (HPV) infection is one of the …

SCancerRNA: Expression at the Single Cell Level and Interaction Resource of Non-coding RNA Biomarkers for Cancers

H Guo, L Zhang, X Cui, L Cheng… - Genomics, Proteomics …, 2024 - academic.oup.com
Non-coding RNAs (ncRNAs) participate in multiple biological processes associated with
cancer as tumor suppressors or oncogenic drivers. Due to their high stability in plasma …

Meta-data analysis to explore the hub of the hub-genes that influence SARS-CoV-2 infections highlighting their pathogenetic processes and drugs repurposing

MP Mosharaf, MK Kibria, MB Hossen, MA Islam… - Vaccines, 2022 - mdpi.com
The pandemic of SARS-CoV-2 infections is a severe threat to human life and the world
economic condition. Although vaccination has reduced the outspread, but still the situation is …

[HTML][HTML] Research progress of circRNA as a biomarker of sepsis: a narrative review

L Qi, Y Yan, B Chen, J Cao, G Liang, P Xu… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Sepsis is an abnormal immune response of our body to infection that can lead
to organ failure and death. Although the research on sepsis has been extensive in the past …

Down‐regulation of hsa‐circ‐0107593 promotes osteogenic differentiation of hADSCs via miR‐20a‐5p/SMAD6 signaling

W Huang, Y Wu, Y Zhao, X Gan, B Zhang, X Cen… - Oral …, 2023 - Wiley Online Library
Objectives Increasing evidence indicated circRNAs were involved in stem cells
osteogenesis differentiation. Herein, we aimed to clarify the role of hsa‐circ‐0107593 during …

Investigating the underlying mechanisms of circular RNAs and their application in clinical research of cervical cancer

J Liu, H Zhu, L Fu, T Xu - Frontiers in Genetics, 2021 - frontiersin.org
Circular RNAs (circRNAs) are non-coding RNA molecules, and these are differentially
expressed in various diseases, including cancer, suggesting that circRNAs can regulate …