Pathophysiology of migraine: a disorder of sensory processing

PJ Goadsby, PR Holland… - Physiological …, 2017 - journals.physiology.org
Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Altered processing of sensory stimuli in patients with migraine

M De Tommaso, A Ambrosini, F Brighina… - Nature Reviews …, 2014 - nature.com
Migraine is a cyclic disorder, in which functional and morphological brain changes fluctuate
over time, culminating periodically in an attack. In the migrainous brain, temporal processing …

An update on migraine: current understanding and future directions

F Puledda, R Messina, PJ Goadsby - Journal of neurology, 2017 - Springer
Migraine is a common brain disorder with high disability rates which involves a series of
abnormal neuronal networks, interacting at different levels of the central and peripheral …

Pathophysiological bases of comorbidity in migraine

C Altamura, I Corbelli, M De Tommaso… - Frontiers in Human …, 2021 - frontiersin.org
Despite that it is commonly accepted that migraine is a disorder of the nervous system with a
prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies …

Cortical spreading depression as a site of origin for migraine: role of CGRP

LN Close, S Eftekhari, M Wang, AC Charles… - …, 2019 - journals.sagepub.com
Premise Migraine is a complex neurologic disorder that leads to significant disability, yet
remains poorly understood. Problem One potential triggering mechanism in migraine with …

Insights into migraine attacks from neuroimaging

R Messina, MA Rocca, PJ Goadsby… - The Lancet Neurology, 2023 - thelancet.com
Migraine is one of the most common neurological diseases and it has a huge social and
personal impact. Although head pain is the core symptom, individuals with migraine can …

Clinical neurophysiology of migraine with aura

G Coppola, C Di Lorenzo, V Parisi, M Lisicki… - The journal of headache …, 2019 - Springer
Background The purpose of this review is to provide a comprehensive overview of the
findings of clinical electrophysiology studies aimed to investigate changes in information …

Resting state connectivity between default mode network and insula encodes acute migraine headache

G Coppola, A Di Renzo, E Tinelli, C Di Lorenzo… - …, 2018 - journals.sagepub.com
Background Previous functional MRI studies have revealed that ongoing clinical pain in
different chronic pain syndromes is directly correlated to the connectivity strength of the …

Increased amplitude of thalamocortical low-frequency oscillations in patients with migraine

DJ Hodkinson, SL Wilcox, R Veggeberg… - Journal of …, 2016 - Soc Neuroscience
For many years, neurobiological theories have emphasized the importance of neuronal
oscillations in the emergence of brain function. At the same time, clinical studies have shown …

White matter changes in chronic and episodic migraine: a diffusion tensor imaging study

Á Planchuelo-Gómez, D García-Azorín… - The journal of headache …, 2020 - Springer
Background White matter alterations have been observed in patients with migraine.
However, no microstructural white matter alterations have been found particularly in …