Primary immunodeficiencies (PID) are disorders that for the most part result from mutations
in genes involved in immune host defense and immunoregulation. These conditions are …

Large outbreaks of acute food-related poisoning, characterized by hepatic sinusoidal
obstruction syndrome, hemorrhagic necrosis, and rapid liver failure, occur on a regular basis …

Summary of Key Recommendations Diagnosis It is recommended that the diagnosis of veno‐
occlusive disease (sinusoidal obstruction syndrome)[VOD (SOS)] be based primarily on …

The transplantation of stem cells from a matched unrelated donor (MUD) or a haploidentical
mismatched related donor (MMRD) is a widely used variant of curative treatment for patients …

Background Further improvement of preparative regimens before allogeneic haemopoietic
stem cell transplantation (HSCT) is an unmet medical need for the growing number of older …

Wiskott–Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency disorder
characterized by the triad of eczema, thrombocytopenia, and severe and often recurrent …

Sixty thalassemia patients (median age, 7 years; range, 1-37) underwent allogeneic
hematopoietic stem cell transplantation (HSCT) after a preparation combining thiotepa …

Chronic granulomatous disease (CGD) can be cured by allogeneic hemopoietic stem cell
transplantation (HSCT). Complications include graft failure, graft-versus-host disease …

Allogeneic hematopoietic cell transplantation (HCT) with myeloablative conditioning for
disorders associated with excessive inflammation such as hemophagocytic …

Deficiency of the purine salvage enzyme adenosine deaminase leads to SCID (ADA-SCID).
Hematopoietic cell transplantation (HCT) can lead to a permanent cure of SCID; however …