An updated review of the biomarkers of response to immune checkpoint inhibitors in Merkel cell carcinoma: Merkel cell carcinoma and immunotherapy

A Fojnica, K Ljuca, S Akhtar, Z Gatalica, S Vranic - Cancers, 2023 - mdpi.com
Simple Summary Merkel cell carcinoma (MCC) is a rare and highly aggressive type of skin
neuroendocrine cancer that frequently recurs and metastasizes within a relatively short …

Merkel cell polyomavirus: infection, genome, transcripts and its role in development of Merkel cell carcinoma

R Houben, B Celikdemir, T Kervarrec, D Schrama - Cancers, 2023 - mdpi.com
Simple Summary By studying the cancer-inducing ability of polyomaviruses, several
milestones in cancer research crucially contributing to our current understanding of, eg, the …

Distinct regulations driving YAP1 expression loss in poroma, porocarcinoma and RB1‐deficient skin carcinoma

T Kervarrec, E Frouin, C Collin, A Tallet… - …, 2023 - Wiley Online Library
Aims Recently, YAP1 fusion genes have been demonstrated in eccrine poroma and
porocarcinoma, and the diagnostic use of YAP1 immunohistochemistry has been …

Analyses of combined Merkel cell carcinomas with neuroblastic components suggests that loss of T antigen expression in Merkel cell carcinoma may result in cell …

T Kervarrec, S Appenzeller, S Gramlich… - The Journal of …, 2024 - Wiley Online Library
Merkel cell carcinoma (MCC) is an aggressive skin cancer frequently caused by genomic
integration of the Merkel cell polyomavirus (MCPyV). MCPyV‐negative cases often present …

Merkel cell carcinoma: an update

RC DeCoste, MD Carter, TY Ly, JR Gruchy… - Human Pathology, 2023 - Elsevier
Merkel cell carcinoma (MCC) is an uncommon primary cutaneous neuroendocrine
carcinoma associated with an adverse prognosis. In recent years, our understanding of …

Combined Merkel Cell Carcinoma and Squamous Cell Carcinoma: A Systematic Review

E Ríos-Viñuela, F Mayo-Martínez, E Nagore… - Cancers, 2024 - mdpi.com
Simple Summary Although considerable advances have been made in the understanding of
the pathogenesis of Merkel cell carcinoma (MCC), many questions remain unanswered …

Current and preclinical treatment options for Merkel cell carcinoma

B Celikdemir, R Houben, T Kervarrec… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Merkel cell carcinoma (MCC) is a rare, highly aggressive form of skin cancer
with neuroendocrine features. The origin of this cancer is still unclear, but research in the …

Changes in categorization or nomenclature within neuroendocrine tumors

GV Trucco, M Volante - Endocrine-Related Cancer, 2024 - erc.bioscientifica.com
Graphical abstract Abstract The 5th edition of the World Health Organization (WHO)
classification of neuroendocrine neoplasms (NENs) is built to achieve a uniform terminology …

Exploring diagnosis and therapeutic complexities of an aggressive Merkel cell carcinoma: A case report and review of the literature

T de Carvalho Kimura, CT Chone, PA Vargas… - Oral Oncology, 2023 - Elsevier
Merkel cell carcinoma (MCC) is an aggressive and rare cutaneous neuroendocrine
carcinoma that predominantly affects the sun-damaged skin of the head and neck region …

Combined Merkel cell carcinoma with nodal presentation: report of a case diagnosed with excisional but not incisional biopsy and literature review

CY Liu, NW Kang, K Takeuchi, SS Chuang - Diagnostics, 2023 - mdpi.com
Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma (NEC) of the skin.
As compared to pure MCCs, combined MCCs are aggressive and exhibit a higher …