[HTML][HTML] Haemonchosis in Sheep and Goats, Control Strategies and Development of Vaccines against Haemonchus contortus

I Adduci, F Sajovitz, B Hinney, K Lichtmannsperger… - Animals, 2022 - mdpi.com
Simple Summary Haemonchus contortus is the most pathogenic blood-feeding parasitic
nematode in sheep and goats, threatening animal welfare and causing tremendous …

[HTML][HTML] Prospects of using high-throughput proteomics to underpin the discovery of animal host–nematode interactions

T Wang, RB Gasser - Pathogens, 2021 - mdpi.com
Parasitic nematodes impose a significant public health burden, and cause major economic
losses to agriculture worldwide. Due to the widespread of anthelmintic resistance and lack of …

[HTML][HTML] H11-induced immunoprotection is predominantly linked to N-glycan moieties during Haemonchus contortus infection

C Wang, L Liu, T Wang, X Liu, W Peng… - Frontiers in …, 2022 - frontiersin.org
Nematodes are one of the largest groups of animals on the planet. Many of them are major
pathogens of humans, animals and plants, and cause destructive diseases and …

[HTML][HTML] Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune …

Z Wen, Y Zhang, J Feng, K Aimulajiang… - Frontiers in …, 2022 - frontiersin.org
Haemonchus contortus is an important parasitic nematode of ruminants. Previous studies
showed that H. contortus escape the immunity through complex mechanisms, including …

An Artemisia cina n-hexane extract reduces the Haemonchus contortus and Teladorsagia circumcincta fecal egg count in naturally infected periparturient goats

RI Higuera-Piedrahita, M Dolores-Hernández… - Tropical Animal Health …, 2022 - Springer
The objective of this study was to evaluate an n-hexane extract of Artemisia cina (Acn-h) as
a natural anthelmintic treatment for periparturient goats naturally infected with the …

[HTML][HTML] In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear …

ZH Wen, XR Xie, MT Aleem, K Aimulajiang, C Chen… - Parasites & …, 2021 - Springer
Abstract Background Trehalose-6-phosphate phosphatase (TPP6) is a key enzyme in the
trehalose biosynthesis pathway. The accumulation of TPP6 inside the body is harmful to the …

[HTML][HTML] Progress and Challenges for Developing Vaccines against Gastrointestinal Nematodes of Ruminants

H Liu, Y Zhang, F Liu, L Ye, X Liu, C Wang, M Hu - Veterinary Vaccine, 2023 - Elsevier
Gastrointestinal nematodes (GINs) infect sheep, goats and cattle, causing huge economic
losses to the breeding industry worldwide. The current major control method is the usage of …

[HTML][HTML] Immunization With Recombinant Haemonchus contortus Y75B8A.8 Partially Protects Local Crossbred Female Goats From Haemonchus contortus Infection

X Tian, M Lu, Y Bu, Y Zhang, K Aimulajiang… - Frontiers in Veterinary …, 2022 - frontiersin.org
Haemonchus contortus Y75B8A. 8 (Hc8) derived from H. contortus excretory–secretory (ES)
products was identified as a functional inhibitor of goat interleukin 2 (IL-2). It may act as a …

Divergent humoral responses between males and females against 24kDa excretory-secretory protein of Haemonchus contortus and influence of ovine β-globin …

CH Okino, SCM Niciura, AP Minho, SN Esteves… - Developmental & …, 2024 - Elsevier
Lambs harboring the Hb-AA β-globin haplotype present improved cell-mediated responses
and increased resistance against Haemonchus contortus infection. The aim of the present …

Biochemical characterization, substrate and stereoselectivity of an outer surface putative α/β hydrolase from the pathogenic Leptospira

UN Shankar, SK Padhi, M Akif - International Journal of Biological …, 2023 - Elsevier
The genome of pathogenic leptospira encodes a plethora of outer surface and secretory
proteins. The outer surface or secreted α/β hydrolases in a few pathogenic organisms are …