In the last decades the approach to cancer patient management has been deeply
revolutionized. We are moving from a “one-fits-all” strategy to the “personalized medicine” …

Astrocytes, which are homeostatic cells of the central nervous system (CNS), display
remarkable heterogeneity in their morphology and function. Besides their physical and …

Tumour‐associated microglia/macrophages (TAM) are the most numerous non‐neoplastic
populations in the tumour microenvironment in glioblastoma multiforme (GBM), the most …

Bone is the one of the most common sites of distant metastasis of solid tumors. Secreted
proteins are known to influence pathological interactions between metastatic cancer cells …

In the brain, levels of inflammatory cytokines, interleukin-1 beta (IL-1β) and tumor necrosis
factor-alpha (TNF-α), are elevated under traumatic brain injury, neuroinflammatory …

Gliomas are the most common type of the malignant brain tumor, which arise from glial cells.
They make up about 40% of all primary brain tumors and around 70% of all primary …

During aggressive tumor growth and migration, glioblastoma cells secrete diverse
molecules and adhesion proteins to the extracellular matrix. Yet, the biochemical effects of …

Purpose Gastric cancer is a commonly occurring cancer in A sia and one of the leading
causes of cancer deaths. However, there is no reliable blood‐based screening test for this …

Clinical proteomics can be defined as the use of proteomic technologies to identify and
measure biomarkers in fluids and tissues. The current work is intended to review various …

The tumor microenvironment including glial cells and their inflammatory products regulates
brain tumor development and progression. We have previously established that human …