In vivo electrochemical sensing based on implantable microelectrodes is a strong driving
force of analytical neurochemistry in brain. The complex and dynamic neurochemical …

Heart failure (HF) is a major public health problem worldwide, especially coronary heart
disease (myocardial infarction)-induced HF with reduced ejection fraction (HFrEF), which …

NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in
proliferation and give rise to myelinating oligodendrocytes during early brain development …

The in‐depth study of single cells requires the dynamically molecular information in one
particular nanometer‐sized organelle in a living cell, which is difficult to achieve using …

The central mechanisms underlying pain chronicity remain elusive. Here, we identify a
reciprocal neuronal circuit in mice between the anterior cingulate cortex (ACC) and the …

Large dense‐core vesicles (LDCVs) are larger in volume than synaptic vesicles, and are
filled with multiple neuropeptides, hormones, and neurotransmitters that participate in …

Synaptotagmins confer calcium-dependence to the exocytosis of secretory vesicles, but how
coexpressed synaptotagmins interact remains unclear. We find that synaptotagmin-1 and …

Visceral hypersensitivity and pain result, at least in part, from increased excitability of
primary afferents that innervate the colon. In addition to intrinsic changes in these neurons …

Neuromodulators such as monoamines are often expressed in neurons that also release at
least one fast-acting neurotransmitter. The release of a combination of transmitters provides …

Current models emphasize that membrane voltage (Vm) depolarization-induced Ca2+ influx
triggers the fusion of vesicles to the plasma membrane. In sympathetic adrenal chromaffin …