Modulating Nitric Oxide: Implications for Cytotoxicity and Cytoprotection

I Belenichev, O Popazova, N Bukhtiyarova… - Antioxidants, 2024 - mdpi.com
Despite the significant progress in the fields of biology, physiology, molecular medicine, and
pharmacology; the designation of the properties of nitrogen monoxide in the regulation of life …

Combined Pharmacological Modulation of Translational and Transcriptional Activity Signaling Pathways as a Promising Therapeutic Approach in Children with …

A Kamenshchyk, I Belenichev, V Oksenych… - Biomolecules, 2024 - mdpi.com
Myocardial hypertrophy is the most common condition that accompanies heart development
in children. Transcriptional gene expression regulating pathways play a critical role both in …

Nitric oxide-dependent mechanism of endothelial dysfunction formation is a promising target link for pharmacological management

IF Belenichev, PG Bak, OO Popazova, NV Bukhtiyarova… - 2022 - dspace.zsmu.edu.ua
Herein, we presented a review to show that the main mechanism underlying endothelial
dysfunction is a decrease in the formation and bioavailability of NO against the background …

Altered Blood Molecular Markers of Cardiovascular Function in Rats after Intrauterine Hypoxia and Drug Therapy

O Popazova, I Belenichev, O Yadlovskyi… - Current Issues in …, 2023 - mdpi.com
Many children and adults who have suffered prenatal hypoxia at an early age develop many
serious diseases. This disease is an actual problem of pediatric cardiology and little studied …

Characteristics of HIF-1α and HSP70 MRNA Expression, Level, and Interleukins in Experimental Chronic Generalized Periodontitis

P Daria, B Igor, K Oleh, R Victor - MicroRNA, 2024 - benthamdirect.com
Objectives: Periodontal diseases are a rather complex problem of modern dentistry and do
not have only medical but also social significance. The objective of this study is to weigh the …

Morpho-functional indicators changes of rats' myocardium in experimental doxorubicin-induced chronic heart failure and its pharmacological modulation with new 4 …

PG Bak, IF Belenichev, LI Kucherenko, AV Abramov… - 2021 - dspace.zsmu.edu.ua
Bromide 1-(β-phenylethyl)-4-amino-1, 2, 4-triazolium (Hypertril) has the properties of a beta-
blocker and of NO-mimetic, is assigned to the IV class of toxicity. All these effects make …

[PDF][PDF] Influence of experimental heart failure therapy with different generations of β-adrenergic blockers on Cardiac Electrical Activity (ECG) and Autonomic …

O Goncharov, I Belenichev, A Abramov… - …, 2023 - pharmacia.pensoft.net
In the complex treatment of chronic heart failure (CHF) β-adrenoblockers (carvedilol,
nebivolol, bisoprolol, metoprolol) are used, which due to their pharmacological properties …

Use of metabolites, metabolithotropic agents and nutritional supplements in sports and sports medicine: a modern view on the problem

IF Bielenichev, NA Gorchakova, EY Doroshenko… - 2023 - dspace.zsmu.edu.ua
Aim. The purpose of this study was to conduct an up-to-date semantic analysis of the results
of our own research and literature data on the medical and pharmacological characteristics …

Integrative and biochemical parameters in rats in the simulation of doxorubicin chronic heart failure and during the use of Β-adrenergic blockers

I Belenichev, P Bak, O Popazova… - Journal of Faculty of …, 2023 - dergipark.org.tr
Objective: In the treatment of chronic heart failure, β-blockers are actively used-Carvedilol,
Nebivolol, Metoprolol, Bisoprolol, etc. However, they have a number of serious adverse …

Indicators of bioelectrical activity of the rat heartafter prenatal hypoxia and pharmacological correction

OO Popazova, IF Belenichev, AV Abramov… - 2022 - dspace.zsmu.edu.ua
Background. Posthypoxic cardiopathy is one of the risk factors for the development of
cardiovascular pathology (rhythm disturbances, vascular dystonia, etc.) in subsequent age …