Understanding viral and immune interplay during vertical transmission of HIV: implications for cure

O Amin, J Powers, KM Bricker, A Chahroudi - Frontiers in Immunology, 2021 - frontiersin.org
Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …

Mother-to-child transmission of HIV: pathogenesis, mechanisms and pathways

AP Kourtis, M Bulterys - Clinics in perinatology, 2010 - perinatology.theclinics.com
Without doubt, one of the greatest medical and public health achievements has been the
significant reduction in mother-to-child transmission (MTCT) of human immunodeficiency …

Salivary secretory leukocyte protease inhibitor is associated with reduced transmission of human immunodeficiency virus type 1 through breast milk

C Farquhar, TC VanCott… - The Journal of …, 2002 - academic.oup.com
Secretory leukocyte protease inhibitor (SLPI), a protein found in saliva, breast milk, and
genital secretions, is capable of inhibiting human immunodeficiency virus (HIV) type 1 in …

High maternal HIV-1 viral load during pregnancy is associated with reduced placental transfer of measles IgG antibody

C Farquhar, R Nduati, N Haigwood… - JAIDS Journal of …, 2005 - journals.lww.com
Background: Studies among HIV-1-infected women have demonstrated reduced placental
transfer of IgG antibodies against measles and other pathogens. As a result, infants born to …

Resistance to HIV infection

M Marmor, K Hertzmark, SM Thomas, PN Halkitis… - Journal of urban …, 2006 - Springer
The biological correlates of an effective immune response that could contain or prevent HIV
infection remain elusive despite substantial scientific accomplishments in understanding the …

Susceptible and protective HLA class 1 alleles against dengue fever and dengue hemorrhagic fever patients in a Malaysian population

R Appanna, S Ponnampalavanar, L Lum Chai See… - PloS one, 2010 - journals.plos.org
Background The human leukocyte antigen alleles have been implicated as probable genetic
markers in predicting the susceptibility and/or protection to severe manifestations of dengue …

HIV-1 diversity versus HLA class I polymorphism

HAF Stephens - Trends in immunology, 2005 - cell.com
HIV-1 is rapidly diversifying in African, Asian and Caucasoid populations, which in parallel
display extensive polymorphism of genes encoding class I human leukocyte antigens (HLA) …

Human leukocyte antigen concordance and the transmission risk via breast-feeding of human T cell lymphotropic virus type I

RJ Biggar, J Ng, N Kim, M Hisada, HC Li… - Journal of Infectious …, 2006 - academic.oup.com
Objective We examined the association between mother-to-child human T cell lymphotropic
virus type I (HTLV-I) transmission and human leukocyte antigen (HLA) class I types Methods …

Maternal HLA homozygosity and mother-child HLA concordance increase the risk of vertical transmission of HIV-1

RD Mackelprang, G John-Stewart… - The Journal of …, 2008 - academic.oup.com
Background Mother-child human leukocyte antigen (HLA) concordance and maternal HLA
homozygosity may increase the risk of vertical transmission of human immunodeficiency …

Association between HLA-G 3′ UTR 14-bp polymorphism and HIV vertical transmission in Brazilian children

A Fabris, E Catamo, L Segat, M Morgutti, LC Arraes… - Aids, 2009 - journals.lww.com
Objectives: The aim of our study was to verify the possible association between an HLA-G
14-bp deletion/insertion polymorphism and perinatal HIV transmission in Brazilian children …