Macrophages are important immune cells in innate immunity, and have remarkable
heterogeneity and polarization. Under pathological conditions, in addition to the resident …

Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Background & Aims Chronic liver disease (CLD) represents a major global health burden.
We undertook this study to identify the factors associated with adverse outcomes in patients …

Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …

Alcoholic liver disease (ALD) is a multifaceted process that involves excessive lipid, reactive
oxygen species (ROS) production, unbalanced mitochondrial homeostasis, and ultimate cell …

Damage-associated molecular patterns (DAMPs) are endogenous molecules that are
released from host cells as a result of cell death or damage. The release of DAMPs in …

Metabolism-associated fatty liver disease (MAFLD) is a multifaceted disease that involves
complex interactions between various organs, including the gut and heart. It is defined by …

Macrophages, as central components of innate immunity, feature significant heterogeneity.
Numerus studies have revealed the pivotal roles of macrophages in the pathogenesis of …

Alcoholic liver disease (ALD) is the most frequent liver disease worldwide, resulting in
severe harm to personal health and posing a serious burden to public health. Based on the …

Excessive alcohol consumption contributes to a broad clinical spectrum of liver diseases,
from simple steatosis to end-stage hepatocellular carcinoma. The liver is the primary organ …