The general secretory (Sec) pathway comprises an essential, ubiquitous and universal
export machinery for most proteins that integrate into, or translocate through, the plasma …

RNA helicases of the DEAD-box protein family have been shown to participate in every
aspect of RNA metabolism. They are present in most organisms where they work as RNA …

In bacteria, two major pathways exist to secrete proteins across the cytoplasmic membrane.
The general Secretion route, termed Sec-pathway, catalyzes the transmembrane …

About 25% to 30% of the bacterial proteins function in the cell envelope or outside of the
cell. These proteins are synthesized in the cytosol, and the vast majority is recognized as a …

Recognition of signal sequences by cognate receptors controls the entry of virtually all
proteins to export pathways. Despite its importance, this process remains poorly understood …

The vast majority of proteins trafficking across or into the bacterial cytoplasmic membrane
occur via the translocon. The translocon consists of the SecYEG complex that forms an …

The conserved protein-conducting channel, referred to as the Sec61 channel in eukaryotes
or the SecY channel in eubacteria and archaea, translocates proteins across cellular …

All cells must traffic proteins across their membranes. This essential process is responsible
for the biogenesis of membranes and cell walls, motility and nutrient scavenging and uptake …

Bacillus subtilis, belonging to the type species of Bacillus, is a type of soil-derived, low% G+
C, endospore-forming Gram-positive bacterium. After the discovery of B. subtilis 168 that …

Gram negative bacteria possess a large variety of protein transport systems, by which
proteins that are synthesised in the cytosol are exported to destinations in the cell envelope …