Therapeutic application of carvacrol: A comprehensive review

M Imran, M Aslam, SA Alsagaby, F Saeed… - Food science & …, 2022 - Wiley Online Library
Carvacrol is a major natural constituent and is significantly present as an essential oil in
aromatic plants and is well known for its numerous biological activities. Therapeutic …

[HTML][HTML] Antimicrobial activity of nanoformulations of carvacrol and thymol: New trend and applications

A Hajibonabi, M Yekani, S Sharifi, JS Nahad, SM Dizaj… - OpenNano, 2023 - Elsevier
Thymol and carvacrol are aromatic compounds derived from plants that exhibit considerable
broad-spectrum antimicrobial effects. They have also shown extensive biological effects …

Effects of polyphenols on oxidative stress, inflammation, and interconnected pathways during spinal cord injury

S Fakhri, F Abbaszadeh, SZ Moradi… - Oxidative medicine …, 2022 - Wiley Online Library
Despite the progression in targeting the complex pathophysiological mechanisms of
neurodegenerative diseases (NDDs) and spinal cord injury (SCI), there is a lack of effective …

Anticancer, antineurodegenerative, antimicrobial, and antidiabetic activities of carvacrol: recent advances and limitations for effective formulations

Q Aljelehawy, Y Maroufi, H Javid… - Nano micro …, 2023 - nmb-journal.com
Bioactive compounds isolated from medicinal plant species can synergize therapeutic
properties of conventional drugs. At this regard, improved biocompatibility and bioavailability …

Carvacrol, a Plant Metabolite Targeting Viral Protease (Mpro) and ACE2 in Host Cells Can Be a Possible Candidate for COVID-19

H Javed, MFN Meeran, NK Jha, S Ojha - Frontiers in Plant Science, 2021 - frontiersin.org
The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
started in December 2019, resulting in the coronavirus disease-19 (COVID-19) pandemic …

Electrospun anti-inflammatory patch loaded with essential oils for wound healing

S Garcia-Salinas, M Evangelopoulos… - International journal of …, 2020 - Elsevier
Wound healing is a complex process that consists of three overlapping phases:
inflammation, proliferation, and remodeling. A bacterial infection can increase inflammation …

Therapeutic effects of extracellular vesicles from human adipose‐derived mesenchymal stem cells on chronic experimental autoimmune encephalomyelitis

M Jafarinia, F Alsahebfosoul, H Salehi… - Journal of cellular …, 2020 - Wiley Online Library
Since in cell therapy, there are always concerns about immune rejection, genetic disability,
and malignancies, special attention has been paid to extracellular vesicles (EVs) which are …

Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages by modulating the ERK1/2 pathway

C Yan, W Kuang, L Jin, R Wang, L Niu, C Xie, J Ding… - Scientific Reports, 2023 - nature.com
Macrophages play an important role in the development of life-threatening sepsis, which is
characterized by multiorgan dysfunction, through their ability to produce inflammatory …

Polyphenols targeting oxidative stress in spinal cord injury: current status and future vision

F Islam, S Bepary, MH Nafady, MR Islam… - Oxidative Medicine …, 2022 - Wiley Online Library
A spinal cord injury (SCI) occurs when the spinal cord is deteriorated or traumatized, leading
to motor and sensory functions lost even totally or partially. An imbalance within the …

Nanotechnology as a tool to improve the biological activity of carvacrol: a review

RL de Souza, AGB Dantas, C de Oliveira Melo… - Journal of Drug Delivery …, 2022 - Elsevier
Carvacrol is a phenolic monoterpenoid found in the essential oil of the Lamiaceae family.
Carvacrol has been applied in many studies, including food preservative and therapeutic …