The study of tumour-specific antigens (TSAs) as targets for antitumour therapies has
accelerated within the past decade. The most commonly studied class of TSAs are those …

Neoantigens are newly formed peptides created from somatic mutations that are capable of
inducing tumor-specific T cell recognition. Recently, researchers and clinicians have …

Effective data sharing is key to accelerating research to improve diagnostic precision,
treatment efficacy, and long-term survival in pediatric cancer and other childhood …

Rhabdoid tumors (RTs) are genomically simple pediatric cancers driven by the biallelic
inactivation of SMARCB1, leading to SWI/SNF chromatin remodeler complex deficiency …

The interest in therapeutic cancer vaccines has caught enormous attention in recent years
due to several breakthroughs in cancer research, among which the finding that successful …

Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

Tumor neoantigens play an important role in current cancer immunotherapies. The most
commonly studied class of tumor neoantigens contains those derived from single-nucleotide …

Background The transcription factor CTCF appears indispensable in defining topologically
associated domain boundaries and maintaining chromatin loop structures within these …

Simple Summary Pediatric sarcomas, including Ewing sarcoma and osteosarcoma, were
first to be treated with an anticancer vaccine 100 years ago. This review moves on from a …

Background Although mutated HLA ligands are considered ideal cancer-specific
immunotherapy targets, evidence for their presentation is lacking in hepatocellular …