RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics
R Chaudhuri, S Bhattacharya, J Dash… - Journal of Medicinal …, 2020 - ACS Publications
Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
Guanine-rich RNA sequences can fold into four-stranded structures, termed G-quadruplexes
(G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated …
(G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated …
Visualization of RNA-quadruplexes in live cells
A Laguerre, K Hukezalie, P Winckler… - Journal of the …, 2015 - ACS Publications
Visualization of DNA and RNA quadruplex formation in human cells was demonstrated
recently with different quadruplex-specific antibodies. Despite the significant interest in these …
recently with different quadruplex-specific antibodies. Despite the significant interest in these …
Applications of guanine quartets in nanotechnology and chemical biology
L Stefan, D Monchaud - Nature Reviews Chemistry, 2019 - nature.com
Guanine and related nucleobases such as guanosine, deoxyguanosine and isoguanosine
are notable molecular tools for designing functional supramolecular assemblies. This …
are notable molecular tools for designing functional supramolecular assemblies. This …
The tale of RNA G-quadruplex
P Agarwala, S Pandey, S Maiti - Organic & biomolecular chemistry, 2015 - pubs.rsc.org
G-quadruplexes are non-canonical secondary structures found in guanine rich regions of
DNA and RNA. Reports have indicated the wide occurrence of RNA G-quadruplexes across …
DNA and RNA. Reports have indicated the wide occurrence of RNA G-quadruplexes across …
A difunctional electrochemiluminescence sensor based on Ru-MOFs and strand-displacement-amplification reaction for ultrasensitive detection of Hg2+ and Ag+
A label free difunctional electrochemiluminescence (ECL) sensor for the ultrasensitive
detection of mercury ions (Hg 2+) and silver ions (Ag+) was constructed based on Ru (bpy) 3 …
detection of mercury ions (Hg 2+) and silver ions (Ag+) was constructed based on Ru (bpy) 3 …
G‐quadruplex structures and their interaction diversity with ligands
S Zhang, Y Wu, W Zhang - ChemMedChem, 2014 - Wiley Online Library
G‐Quadruplexes are distinct nucleic acid secondary structures that are formed from G‐rich
DNA and RNA sequences; they are built around successive G‐tetrads of Hoogsteen …
DNA and RNA sequences; they are built around successive G‐tetrads of Hoogsteen …
Mesoporous silica containers and programmed catalytic hairpin assembly/hybridization chain reaction based electrochemical sensing platform for MicroRNA …
H Cheng, W Li, S Duan, J Peng, J Liu, W Ma… - Analytical …, 2019 - ACS Publications
In this work, based on mesoporous silica containers (MSNs) with the programmed enzyme-
free DNA assembly amplification of catalytic hairpin assembly (CHA) and hybridization chain …
free DNA assembly amplification of catalytic hairpin assembly (CHA) and hybridization chain …
Structure, properties, and biological relevance of the DNA and RNA G-quadruplexes: Overview 50 years after their discovery
NG Dolinnaya, AM Ogloblina, MG Yakubovskaya - Biochemistry (Moscow), 2016 - Springer
Abstract G-quadruplexes (G4s), which are known to have important roles in regulation of key
biological processes in both normal and pathological cells, are the most actively studied non …
biological processes in both normal and pathological cells, are the most actively studied non …