Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission

ROM Rego, JJA Trentelman, J Anguita, AM Nijhof… - Parasites & vectors, 2019 - Springer
Hematophagous arthropods are responsible for the transmission of a variety of pathogens
that cause disease in humans and animals. Ticks of the Ixodes ricinus complex are vectors …

Strategies for detecting rickettsiae and diagnosing rickettsial diseases

A Luce-Fedrow, K Mullins, AP Kostik… - Future …, 2015 - Taylor & Francis
Rickettsial diseases and scrub typhus constitute a group of the oldest known vector-borne
diseases. The cosmopolitan distribution of the vectors that transmit rickettsiae and orientiae …

[HTML][HTML] Comparative vertical transmission of Rickettsia by Dermacentor variabilis and Amblyomma maculatum

EK Harris, VI Verhoeve, KH Banajee… - Ticks and tick-borne …, 2017 - Elsevier
The geographical overlap of multiple Rickettsia and tick species coincides with the
molecular detection of a variety of rickettsial agents in what may be novel tick hosts …

V‐ATPase subunit a is required for survival and midgut development of Locusta migratoria

XJ Liu, XY Liang, J Guo, XK Shi… - Insect Molecular …, 2022 - Wiley Online Library
The vacuolar‐type H+‐ATPase (V‐ATPase) is an ATP‐dependent proton pump, which
regulates various cellular processes. To date, most functional studies on V‐ATPases of …

ATP-sensitive inward rectifier potassium channels regulate secretion of pro-feeding salivary proteins in the lone star tick (Amblyomma americanum)

Z Li, S McComic, R Chen, WTH Kim… - International Journal of …, 2023 - Elsevier
Understanding the physiological and molecular regulation of tick feeding is necessary for
developing intervention strategies to curb disease transmission by ticks. Pharmacological …

Identification and Characterization of a Relish-type NF-κB, DvRelish, in Dermacentor variabilis in Response to Rickettsia rickettsii Infection

C Fongsaran, VI Verhoeve, K Jirakanwisal… - Frontiers in Cellular …, 2024 - frontiersin.org
Ixodid ticks serve as hosts and transmission vectors for several obligate intracellular
bacteria, including members of the spotted fever group of Rickettsia. Although ticks generate …

Amblyomma maculatum Feeding Augments Rickettsia parkeri Infection in a Rhesus Macaque Model: A Pilot Study

KH Banajee, ME Embers, IM Langohr, LA Doyle… - PLoS …, 2015 - journals.plos.org
Rickettsia parkeri is an emerging eschar-causing human pathogen in the spotted fever
group of Rickettsia and is transmitted by the Gulf coast tick, Amblyomma maculatum. Tick …

Isolate-Dependent Differences in Clinical, Pathological, and Transcriptional Profiles following In Vitro and In Vivo Infections with Rickettsia rickettsii

MFBM Galletti, CD Paddock, JA Hecht… - Infection and …, 2021 - Am Soc Microbiol
Rickettsia rickettsii, the etiological agent of Rocky Mountain spotted fever (RMSF), a life-
threatening tick-borne disease that affects humans and various animal species, has been …

Effect of Amblyomma maculatum (Acari: Ixodidae) Saliva on the Acute Cutaneous Immune Response to Rickettsia parkeri Infection in a Murine Model

KH Banajee, VI Verhoeve, EK Harris… - Journal of medical …, 2016 - academic.oup.com
Abstract Rickettsia parkeri Luckman (Rickettsiales: Rickettsiaceae) is a pathogenic spotted
fever group Rickettsia transmitted by Amblyomma maculatum Koch (Acari: Ixodidae) in the …

Novel Identification of Dermacentor variabilis Arp2/3 Complex and Its Role in Rickettsial Infection of the Arthropod Vector

N Petchampai, P Sunyakumthorn, ML Guillotte… - PLoS …, 2014 - journals.plos.org
Tick-borne spotted fever group (SFG) Rickettsia species must be able to infect both
vertebrate and arthropod host cells. The host actin-related protein 2/3 (Arp2/3) complex is …