Dynamic reorganization of the actin cytoskeleton is fundamental to a number of cell
biological events. A variety of actin-regulatory proteins modulate polymerization and …

Following spinal cord injury (SCI), most axons fail to regenerate and instead form large,
swollen endings generically called 'retraction bulbs.'These endings form and persist after …

Prion diseases typically have long pre-clinical incubation periods during which time the
infectious prion particle and infectivity steadily propagate in the brain. Abnormal neuritic …

The growth cone is an essential structure for nerve growth. Although its membrane and
cytoskeleton are likely to interact coordinately during nerve growth, the mechanisms are …

Exercise intensity is known to affect neuroplasticity. Although corticosterone and lactate
levels have been linked to neuroplasticity, the effect of different endurance exercise intensity …

Cyclase-associated proteins (CAPs) are evolutionary-conserved actin-binding proteins with
crucial functions in regulating actin dynamics, the spatiotemporally controlled assembly and …

Synapses serve as the points of communication between neurons, consisting primarily of
three components: the presynaptic membrane, synaptic cleft, and postsynaptic membrane …

Abstract Background Gangliogliomas (GGs) primary to brainstem are rare, with the
overwhelming majority of GGs occurring in supratentorial, especially temporal lobe …

Actin remodeling is crucial for dendritic spine development, morphology and density. CAP2
is a regulator of actin dynamics through sequestering G-actin and severing F-actin. In a …

The growth cone, which is a unique structure with high motility that forms at the tips of
extending axons and dendrites, is crucial to neuronal network formation. Axonal growth of …