Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect
S Liu, Y Zhang, Y Liu, W Wang, S Gao, W Yuan… - British Journal of …, 2023 - nature.com
Cancer immunotherapy (CIT) has gained increasing attention and made promising progress
in recent years, especially immune checkpoint inhibitors such as antibodies blocking …
in recent years, especially immune checkpoint inhibitors such as antibodies blocking …
Making waves: how ultrasound-targeted drug delivery is changing pharmaceutical approaches
Administration of drugs through oral and intravenous routes is a mainstay of modern
medicine, but this approach suffers from limitations associated with off-target side effects and …
medicine, but this approach suffers from limitations associated with off-target side effects and …
Ultrasound and nanomaterial: an efficient pair to fight cancer
E Alphandéry - Journal of Nanobiotechnology, 2022 - Springer
Ultrasounds are often used in cancer treatment protocols, eg to collect tumor tissues in the
right location using ultrasound-guided biopsy, to image the region of the tumor using more …
right location using ultrasound-guided biopsy, to image the region of the tumor using more …
[HTML][HTML] From concept to early clinical trials: 30 years of microbubble-based ultrasound-mediated drug delivery research
A Bouakaz, JM Escoffre - Advanced Drug Delivery Reviews, 2024 - Elsevier
Ultrasound mediated drug delivery, a promising therapeutic modality, has evolved
remarkably over the past three decades. Initially designed to enhance contrast in ultrasound …
remarkably over the past three decades. Initially designed to enhance contrast in ultrasound …
Landscape of cellular bioeffects triggered by ultrasound-induced sonoporation
D Przystupski, M Ussowicz - International journal of molecular sciences, 2022 - mdpi.com
Sonoporation is the process of transient pore formation in the cell membrane triggered by
ultrasound (US). Numerous studies have provided us with firm evidence that sonoporation …
ultrasound (US). Numerous studies have provided us with firm evidence that sonoporation …
Delivering the CRISPR/Cas9 system for engineering gene therapies: Recent cargo and delivery approaches for clinical translation
RA Foley, RA Sims, EC Duggan, JK Olmedo… - … in Bioengineering and …, 2022 - frontiersin.org
Clustered Regularly Interspaced Short Palindromic Repeats associated protein 9
(CRISPR/Cas9) has transformed our ability to edit the human genome selectively. This …
(CRISPR/Cas9) has transformed our ability to edit the human genome selectively. This …
[HTML][HTML] Focused ultrasound hyperthermia augments release of glioma-derived extracellular vesicles with differential immunomodulatory capacity
Background: Increasing evidence points to the critical role of extracellular vesicles (EVs) as
molecular parcels that carry a diverse array of bioactive payloads for coordination of …
molecular parcels that carry a diverse array of bioactive payloads for coordination of …
Immunotheranostic microbubbles (iMBs)-a modular platform for dendritic cell vaccine delivery applied to breast cancer immunotherapy
Background Therapeutic strategies engaging the immune system against malignant cells
have revolutionized the field of oncology. Proficiency of dendritic cells (DCs) for antigen …
have revolutionized the field of oncology. Proficiency of dendritic cells (DCs) for antigen …
Delivery of anti-cancer drugs using microbubble-assisted ultrasound in digestive oncology: from preclinical to clinical studies
JM Escoffre, N Sekkat, E Oujagir, S Bodard… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The combination of microbubbles (MBs) and ultrasound (US) is an emerging
method for the noninvasive and targeted enhancement of intratumor chemotherapeutic …
method for the noninvasive and targeted enhancement of intratumor chemotherapeutic …
[HTML][HTML] Calcium ion delivery by microbubble-assisted sonoporation stimulates cell death in human gastrointestinal cancer cells
D Przystupski, D Baczyńska, J Rossowska… - Biomedicine & …, 2024 - Elsevier
Ultrasound-mediated cell membrane permeabilization–sonoporation, enhances drug
delivery directly to tumor sites while reducing systemic side effects. The potential of …
delivery directly to tumor sites while reducing systemic side effects. The potential of …