[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Integrating DNA nanotechnology with aptamers for biological and biomedical applications

Z Huang, L Qiu, T Zhang, W Tan - Matter, 2021 - cell.com
In addition to critical biological roles, DNA is also considered an excellent engineering
material with unique characteristics of high programmability and addressability. Recent …

Bioorthogonal disassembly of hierarchical DNAzyme nanogel for high-performance intracellular microRNA imaging

J Shang, S Yu, R Li, Y He, Y Wang, F Wang - Nano Letters, 2023 - ACS Publications
Rolling circle amplification (RCA) enables the facile construction of compact and versatile
DNA nanoassemblies which are yet rarely explored for intracellular analysis. This is might …

DNA nanotechnology approaches for microRNA detection and diagnosis

AR Chandrasekaran, JA Punnoose, L Zhou… - Nucleic acids …, 2019 - academic.oup.com
MicroRNAs are involved in the crucial processes of development and diseases and have
emerged as a new class of biomarkers. The field of DNA nanotechnology has shown great …

Cancer cell membrane camouflaged nanoprobe for catalytic ratiometric photoacoustic imaging of MicroRNA in living mice

K Zhang, X Meng, Z Yang, Y Cao, Y Cheng… - Advanced …, 2019 - Wiley Online Library
Herein, a cancer cell (MCF‐7 cell) membrane‐encapsulated dendritic mesoporous silica
nanoparticle simultaneously functionalized with DNA‐photoacoustic (DNA‐PA) probes and …

Attomolar analyte sensing techniques (AttoSens): a review on a decade of progress on chemical and biosensing nanoplatforms

SP Usha, H Manoharan, R Deshmukh… - Chemical Society …, 2021 - pubs.rsc.org
Detecting the ultra-low abundance of analytes in real-life samples, such as biological fluids,
water, soil, and food, requires the design and development of high-performance biosensing …

DNA tetrahedral nanostructure-based electrochemical miRNA biosensor for simultaneous detection of multiple miRNAs in pancreatic carcinoma

D Zeng, Z Wang, Z Meng, P Wang, L San… - … applied materials & …, 2017 - ACS Publications
Specific and sensitive biomarker detection is essential to early cancer diagnosis. In this
study, we demonstrate an ultrasensitive electrochemical biosensor with the ability to detect …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

AgInZnS quantum dots as anodic emitters with strong and stable electrochemiluminescence for biosensing application

Z Ye, Y Liu, M Pan, X Tao, Y Chen, P Ma, Y Zhuo… - Biosensors and …, 2023 - Elsevier
Quantum dots (QDs) have become promising electrochemiluminescence (ECL) emitters with
high quantum yield and size-tunable luminescence. However, most QDs generate strong …

Electrochemical biosensor based on tetrahedral DNA nanostructures and G-quadruplex–hemin conformation for the ultrasensitive detection of MicroRNA-21 in serum

J Lu, J Wang, X Hu, E Gyimah, S Yakubu… - Analytical …, 2019 - ACS Publications
MicroRNAs (miRNAs) play important roles as significant biomarkers in disease diagnostics.
Here, an electrochemical biosensor was developed for the quick, sensitive, and specific …