Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics

M Wallen, F Aqil, W Spencer, RC Gupta - Cancer letters, 2023 - Elsevier
Chemotherapeutics continue to play a central role in the treatment of a wide variety of
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …

Clinical impact of exosomes in colorectal cancer metastasis

S Ghosh, R Dhar, G Gurudas Shivji, D Dey… - ACS Applied Bio …, 2023 - ACS Publications
Cancer is a complex deadly disease that has caused a global health crisis in recent epochs.
Colorectal cancer (CRC) is the third most common malignant gastrointestinal disease. It has …

[HTML][HTML] Tumor-targeted exosomes for delivery of anticancer drugs

R Raguraman, D Bhavsar, D Kim, X Ren, V Sikavitsas… - Cancer letters, 2023 - Elsevier
Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …

[HTML][HTML] Hyaluronic acid-coated bovine milk exosomes for achieving tumor-specific intracellular delivery of miRNA-204

D Li, L Gong, H Lin, S Yao, Y Yin, Z Zhou, J Shi, Z Wu… - Cells, 2022 - mdpi.com
Cell type-specific drug delivery is a straightforward strategy to achieve targeted cancer
therapy and reduce side effects. Hyaluronic acid (HA), an US Food and Drug Administration …

Exosomes as a drug delivery tool for cancer therapy: A new era for existing drugs and oncolytic viruses

Y Kakiuchi, S Kuroda, N Kanaya… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Exosomes are cell-derived nanovesicles involved in cell-to-cell
communications. These nanovesicles are generally considered to contain important carriers …

[HTML][HTML] Characterization of lipid-based nanomedicines at the single-particle level

C Chen, C Chen, Y Li, R Gu, X Yan - Fundamental Research, 2023 - Elsevier
Abstract Lipid-based nanomedicines (LBNMs), including liposomes, lipid nanoparticles
(LNPs) and extracellular vesicles (EVs), are recognized as one of the most clinically …

Nanotherapeutics in Women's Health Emerging Nanotechnologies for Triple‐Negative Breast Cancer Treatment

S Torres Quintas, A Canha‐Borges, MJ Oliveira… - Small, 2023 - Wiley Online Library
Breast cancer appears as the major cause of cancer‐related deaths in women, with more
than 2 260 000 cases reported worldwide in 2020, resulting in 684 996 deaths. Triple …

[HTML][HTML] Application of milk exosomes for musculoskeletal health: talking points in recent outcomes

NH Kim, J Kim, JY Lee, HA Bae, CY Kim - Nutrients, 2023 - mdpi.com
Milk is a nutrient-rich food source, and among the various milks, breast milk is a nutrient
source provided by mothers to newborns in many mammals. Exosomes are nano-sized …

[HTML][HTML] Multifunctional milk-derived small extracellular vesicles and their biomedical applications

Y Zhong, X Wang, X Zhao, J Shen, X Wu, P Gao… - Pharmaceutics, 2023 - mdpi.com
In recent years, small extracellular vesicles (sEVs) have been regarded as the next
generation of novel delivery systems after lipid nanoparticles because of their advantages …

[HTML][HTML] Potential therapeutic effects of milk-derived exosomes on intestinal diseases

Z Cui, FK Amevor, X Zhao, C Mou, J Pang… - Journal of …, 2023 - Springer
Exosomes are extracellular vesicles with the diameter of 30~ 150 nm, and are widely
involved in intercellular communication, disease diagnosis and drug delivery carriers for …