Pharmacological activity and mechanism of tanshinone IIA in related diseases

R Guo, L Li, J Su, S Li, SE Duncan, Z Liu… - Drug Design …, 2020 - Taylor & Francis
Salvia miltiorrhiza:(Danshen) is a significant (traditional Chinese medication) natural
remedy, enhancing blood circulation and clear blood stasis. In this view, it is widely used …

Impact of cholesterol metabolism in immune cell function and atherosclerosis

M Aguilar-Ballester, A Herrero-Cervera, Á Vinué… - Nutrients, 2020 - mdpi.com
Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity
and is a precursor of bile acids, oxysterols, and steroid hormones. Cholesterol in the body is …

Inflammatory cells in atherosclerosis

M Mehu, CA Narasimhulu, DK Singla - Antioxidants, 2022 - mdpi.com
Atherosclerosis is a chronic progressive disease that involves damage to the intima,
inflammatory cell recruitment and the accumulation of lipids followed by calcification and …

Salvia miltiorrhiza: a potential red light to the development of cardiovascular diseases

L Wang, R Ma, C Liu, H Liu, R Zhu… - Current …, 2017 - ingentaconnect.com
Salvia miltiorrhiza Bunge, also known as Danshen in Chinese, has been widely used to treat
cardiovascular diseases (CVD) in China and other Asia countries. Here, we summarize …

Macrophage polarization in response to epigenetic modifiers during infection and inflammation

U Patel, S Rajasingh, S Samanta, T Cao, B Dawn… - Drug discovery today, 2017 - Elsevier
Highlights•This review is focusing on polarization of macrophages by epigenetic
modifications.•M1/M2 macrophages are flawlessly synchronized, specialized, and perform …

[HTML][HTML] Araloside C attenuates atherosclerosis by modulating macrophage polarization via Sirt1-mediated autophagy

Y Luo, S Lu, Y Gao, K Yang, D Wu, X Xu, G Sun… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Atherosclerosis-related cardiovascular disease is still the predominant cause of death
worldwide. Araloside C (AsC), a natural saponin, exerts extensive anti-inflammatory …

Exosomes: multifaceted messengers in atherosclerosis

H Wang, Y Xie, AM Salvador, Z Zhang, K Chen… - Current Atherosclerosis …, 2020 - Springer
Abstract Purpose of Review Atherosclerosis (AS) is a chronic inflammatory disease that
contributes to the development of coronary artery disease, which has become a leading …

[HTML][HTML] The influence of oxidative stress and autophagy cross regulation on pregnancy outcome

BR de Andrade Ramos, SS Witkin - Cell Stress and Chaperones, 2016 - Elsevier
The generation of reactive oxygen species (ROS), a byproduct of aerobic energy
metabolism, is maintained at physiological levels by the activity of antioxidant components …

[HTML][HTML] Chemical composition of circulating native and desialylated low density lipoprotein: what is the difference?

VI Alipov, VN Sukhorukov, VP Karagodin… - Vessel Plus, 2017 - oaepublish.com
Atherosclerosis and related cardiovascular disorders remain the leading global cause of
morbidity and mortality. Modified low density lipoprotein (LDL) is considered to play a crucial …

AIBP reduces atherosclerosis by promoting reverse cholesterol transport and ameliorating inflammation in apoE−/− mice

M Zhang, GJ Zhao, F Yao, XD Xia, D Gong, ZW Zhao… - Atherosclerosis, 2018 - Elsevier
Background and aims ApoA-1 binding protein (AIBP) is a secreted protein that interacts with
apoA-I and accelerates cholesterol efflux from cells. We have recently reported that AIBP …