[HTML][HTML] Lights, fiber, action! A primer on in vivo fiber photometry

EH Simpson, T Akam, T Patriarchi, M Blanco-Pozo… - Neuron, 2024 - cell.com
Fiber photometry is a key technique for characterizing brain-behavior relationships in vivo.
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …

[HTML][HTML] The locus coeruleus broadcasts prediction errors across the cortex to promote sensorimotor plasticity

R Jordan, GB Keller - Elife, 2023 - elifesciences.org
Prediction errors are differences between expected and actual sensory input and are
thought to be key computational signals that drive learning related plasticity. One way that …

Heterogeneous organization of Locus coeruleus: An intrinsic mechanism for functional complexity

H Ma, H Zhang, Z Zuo, Y Liu - Physiology & Behavior, 2023 - Elsevier
Locus coeruleus (LC) is a small nucleus located deep in the brainstem that contains the
majority of central noradrenergic neurons, which provide the primary source of …

[HTML][HTML] A dopaminergic reward prediction error signal shapes maternal behavior in mice

Y Xie, L Huang, A Corona, AH Pagliaro, SD Shea - Neuron, 2023 - cell.com
How social contact is perceived as rewarding and subsequently modifies interactions is
unclear. Dopamine (DA) from the ventral tegmental area (VTA) regulates sociality, but the …

[HTML][HTML] A circuit from the locus coeruleus to the anterior cingulate cortex modulates offspring interactions in mice

A Corona, J Choe, R Muñoz-Castañeda, P Osten… - Cell reports, 2023 - cell.com
Social sensitivity to other individuals in distress is crucial for survival. The anterior cingulate
cortex (ACC) is a structure involved in making behavioral choices and is influenced by …

Selective deletion of Methyl CpG binding protein 2 from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in mice

DD Rupert, AH Pagliaro, J Choe… - Journal of …, 2023 - Soc Neuroscience
Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome. MECP2 codes
for methyl CpG binding protein 2 (MECP2), a transcriptional regulator that activates genetic …

Shining light on the noradrenergic system

E Tanguay, SJ Bouchard, M Lévesque… - …, 2023 - spiedigitallibrary.org
Despite decades of research on the noradrenergic system, our understanding of its impact
on brain function and behavior remains incomplete. Traditional recording techniques are …

Plasticity in auditory cortex during parenthood

B Haimson, A Mizrahi - Hearing Research, 2023 - Elsevier
Most animals display robust parental behaviors that support the survival and well-being of
their offspring. The manifestation of parental behaviors is accompanied by physiological and …

Multidimensional analysis of a social behavior identifies regression and phenotypic heterogeneity in a female mouse model for Rett syndrome

M Mykins, B Bridges, A Jo, K Krishnan - Journal of Neuroscience, 2024 - Soc Neuroscience
Regression is a key feature of neurodevelopmental disorders such as autism spectrum
disorder, Fragile X syndrome, and Rett syndrome (RTT). RTT is caused by mutations in the X …

Locus coeruleus-noradrenergic neurons regulate stress coping during subchronic exposure to social threats: a characteristic feature in postpartum female mice

A Nakamura, Y Muroi, T Ishii - Cellular and Molecular Neurobiology, 2023 - Springer
Stress-coping strategies have been implicated in depression. The control of stress coping
may improve the symptom and higher prevalence of depression during the postpartum …