Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA. 5

B Imbiakha, S Ezzatpour, DW Buchholz, J Sahler… - Science …, 2023 - science.org
Pathology studies of SARS-CoV-2 Omicron variants of concern (VOC) are challenged by the
lack of pathogenic animal models. While Omicron BA. 1 and BA. 2 replicate in K18-hACE2 …

The role of neutrophil in COVID-19: positive or negative

N Rong, X Wei, J Liu - Journal of Innate Immunity, 2024 - karger.com
The Role of Neutrophil in COVID-19 — Positive or Negative Page 1 J Innate Immun , DOI:
10.1159/000535541 Received: September 16, 2023 Accepted: November 27, 2023 Published …

Generation of a lethal mouse model expressing human ACE2 and TMPRSS2 for SARS-CoV-2 infection and pathogenesis

GU Jeong, I Hwang, W Lee, JH Choi… - … & Molecular Medicine, 2024 - nature.com
Mouse models expressing human ACE2 for coronavirus disease 2019 have been frequently
used to understand its pathogenesis and develop therapeutic strategies against SARS-CoV …

Virus‐Induced Host Chemokine CCL2 in COVID‐19 Pathogenesis: Potential Prognostic Marker and Target of Anti‐Inflammatory Strategy

AW Ansari, F Ahmad, MA Alam… - Reviews in Medical …, 2024 - Wiley Online Library
ABSTRACT A wide variety of inflammatory mediators, mainly cytokines and chemokines, are
induced during SARS CoV‐2 infection. Among these proinflammatory mediators …