Our incomplete understanding of the causes and pathways involved in the onset and
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …

Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is the
most recently defined inflammatory demyelinating disease of the central nervous system …

The term 'neuromyelitis optica spectrum disorders'(NMOSD) is used as an umbrella term that
refers to aquaporin-4 immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica (NMO) …

Importance Myelin oligodendrocyte glycoprotein-IgG1–associated disorder (MOGAD) is a
distinct central nervous system–demyelinating disease. Positive results on MOG-IgG1 …

Recent data suggest that multiple sclerosis white matter lesions surrounded by a rim of iron
containing microglia, termed iron rim lesions, signify patients with more severe disease …

Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Background and Objective There are few studies comparing lesion evolution across different
CNS demyelinating diseases, yet knowledge of this may be important for diagnosis and …

Accurate diagnosis of multiple sclerosis requires careful attention to its differential diagnosis—
many disorders can mimic the clinical manifestations and paraclinical findings of this …

Background and Objectives Relapsing-remitting multiple sclerosis (RRMS), aquaporin-4
antibody–positive neuromyelitis optica spectrum disorder (AQP4-NMOSD), and myelin …