Atypical hemolytic–uremic syndrome

M Noris, G Remuzzi - New England Journal of Medicine, 2009 - Mass Medical Soc
The hemolytic–uremic syndrome, which is characterized by nonimmune hemolytic anemia,
thrombocytopenia, and renal impairment, occurs most frequently in young children. Most …

Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome

PI Tarr, CA Gordon, WL Chandler - The lancet, 2005 - thelancet.com
Most cases of diarrhoea-associated haemolytic uraemic syndrome (HUS) are caused by
Shiga-toxin-producing bacteria; the pathophysiology differs from that of thrombotic …

Thrombotic microangiopathies

JL Moake - New England Journal of Medicine, 2002 - Mass Medical Soc
Thrombotic Microangiopathies | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Combined complement gene mutations in atypical hemolytic uremic syndrome influence clinical phenotype

E Bresin, E Rurali, J Caprioli… - Journal of the …, 2013 - journals.lww.com
Several abnormalities in complement genes reportedly contribute to atypical hemolytic
uremic syndrome (aHUS), but incomplete penetrance suggests that additional factors are …

[HTML][HTML] Atypical hemolytic uremic syndrome

D Kavanagh, TH Goodship, A Richards - Seminars in nephrology, 2013 - Elsevier
Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia,
thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease …

Anaemia in pregnancy

M Goonewardene, M Shehata, A Hamad - Best practice & research Clinical …, 2012 - Elsevier
Anaemia in pregnancy, defined as a haemoglobin concentration (Hb)< 110 g/L, affects more
than 56 million women globally, two thirds of them being from Asia. Multiple factors lead to …

[HTML][HTML] An update for atypical haemolytic uraemic syndrome: diagnosis and treatment. A consensus document

JM Campistol, M Arias, G Ariceta, M Blasco… - Nefrología (English …, 2015 - Elsevier
Haemolytic uraemic syndrome (HUS) is a clinical entity defined as the triad of nonimmune
haemolytic anaemia, thrombocytopenia, and acute renal failure, in which the underlying …

Complement control protein factor H: the good, the bad, and the inadequate

VP Ferreira, MK Pangburn, C Cortés - Molecular immunology, 2010 - Elsevier
The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …

Thrombomodulin mutations in atypical hemolytic–uremic syndrome

M Delvaeye, M Noris, A De Vriese… - … England Journal of …, 2009 - Mass Medical Soc
Background The hemolytic–uremic syndrome consists of the triad of microangiopathic
hemolytic anemia, thrombocytopenia, and renal failure. The common form of the syndrome …

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome

J Caprioli, M Noris, S Brioschi, G Pianetti, F Castelletti… - Blood, 2006 - ashpublications.org
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy with manifestations of
hemolytic anemia, thrombocytopenia, and renal impairment. Genetic studies have shown …