Glutarate is an important C5 linear chain dicarboxylic acid having wide applications in
chemical industry. In this work we report glutarate production by Escherichia coli with a …

Adipic acid is an important monomer in the synthesis of nylon-6, 6. In recent years, the
biosynthesis of adipic acid has received more and more attention. The pathway with l-lysine …

propanediol oxidoreductase (DhaT) of Klebsiella pneumoniae converts 3-
hydroxypropionaldehyde (3-HPA) to 1, 3-propanediol (1, 3-PD) during microbial production …

17α-ethinylestradiol (EE2), a synthetically derived analogue of endogenous estrogen, is
widely employed as a hormonal contraceptive and is recognized as a highly hazardous …

Abstract Production of 2-hydroxybutyric acid (2-HBA) was attempted in recombinant
Escherichia coli W3110 Δtdh ΔilvIH (over) expressing a homologous and mutated threonine …

Pathway engineering is commonly employed to improve the production of various
metabolites but may incur in bottlenecks due to the low catalytic activity of a particular …