The on‐again, off‐again relationship between mitochondrial genomes and species boundaries

DB Sloan, JC Havird, J Sharbrough - Molecular ecology, 2017 - Wiley Online Library
The study of reproductive isolation and species barriers frequently focuses on mitochondrial
genomes and has produced two alternative and almost diametrically opposed narratives. On …

Cytonuclear integration and co-evolution

DB Sloan, JM Warren, AM Williams, Z Wu… - Nature Reviews …, 2018 - nature.com
The partitioning of genetic material between the nucleus and cytoplasmic (mitochondrial and
plastid) genomes within eukaryotic cells necessitates coordinated integration between these …

Inheritance through the cytoplasm

MF Camus, B Alexander-Lawrie, J Sharbrough… - Heredity, 2022 - nature.com
Most heritable information in eukaryotic cells is encoded in the nuclear genome, with
inheritance patterns following classic Mendelian segregation. Genomes residing in the …

Mutation pressure, drift, and the pace of molecular coevolution

M Lynch - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Most aspects of the molecular biology of cells involve tightly coordinated intermolecular
interactions requiring specific recognition at the nucleotide and/or amino acid levels. This …

Assessing the fitness consequences of mitonuclear interactions in natural populations

GE Hill, JC Havird, DB Sloan, RS Burton… - Biological …, 2019 - Wiley Online Library
Metazoans exist only with a continuous and rich supply of chemical energy from oxidative
phosphorylation in mitochondria. The oxidative phosphorylation machinery that mediates …

Mitonuclear coevolution as the genesis of speciation and the mitochondrial DNA barcode gap

GE Hill - Ecology and evolution, 2016 - Wiley Online Library
Mitochondrial genes are widely used in taxonomy and systematics because high mutation
rates lead to rapid sequence divergence and because such changes have long been …

The mitonuclear compatibility species concept

GE Hill - The Auk: Ornithological Advances, 2017 - academic.oup.com
The avian world is packaged into genetic assemblages that we call species. Although
ornithologists can, with a few important exceptions, agree on the boundaries among avian …

Mitonuclear compensatory coevolution

GE Hill - Trends in Genetics, 2020 - cell.com
In bilaterian animals, the mitochondrial genome is small, haploid, does not typically
recombine, and is subject to accumulation of deleterious alleles via Muller's ratchet. These …

[PDF][PDF] Genomic signatures of mitonuclear coevolution in mammals

RJ Weaver, S Rabinowitz, K Thueson… - Molecular Biology and …, 2022 - academic.oup.com
Mitochondrial (mt) and nuclear-encoded proteins are integrated in aerobic respiration,
requiring co-functionality among gene products from fundamentally different genomes …

Genome copy number predicts extreme evolutionary rate variation in plant mitochondrial DNA

KD Zwonitzer, LG Tressel, Z Wu… - Proceedings of the …, 2024 - National Acad Sciences
Nuclear and organellar genomes can evolve at vastly different rates despite occupying the
same cell. In most bilaterian animals, mitochondrial DNA (mtDNA) evolves faster than …