Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

A renewed interest in the characteristics and neural basis of corneal and conjunctival
sensations is developing in recent years due to the high incidence of discomfort and altered …

The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …

Among all adult somatic stem cells, those of the corneal epithelium are unique in their
exclusive location in a defined limbal structure termed Palisades of Vogt. As a result …

Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …

Because vision plays a critical role in obtaining information from the external world,
evolutionary development has provided the structures that sustain this function with special …

Ocular irritation and pain are associated with many clinical situations (eg accidental injury,
eye diseases, surgery and contact lens wearing). Pain and related ocular sensations begin …

This paper outlines changes to the ocular surface caused by contact lenses and their degree
of clinical significance. Substantial research and development to improve oxygen …

purpose. To study the sensations evoked by selective mechanical, chemical, and thermal
stimulation of the conjunctiva and compare them with those elicited by similar stimulation of …

The limbus is a transition from the cornea to conjunctiva and sclera. In human eyes, this thin
strip has a rich variation of tissue structures and composition, typifying a change from scleral …