[HTML][HTML] Noroviruses—the state of the art, nearly fifty years after their initial discovery
LF Ludwig-Begall, A Mauroy, E Thiry - Viruses, 2021 - mdpi.com
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here,
we provide an overview of notable advances in norovirus research and provide a short …
we provide an overview of notable advances in norovirus research and provide a short …
[HTML][HTML] Favipiravir elicits antiviral mutagenesis during virus replication in vivo
Lethal mutagenesis has emerged as a novel potential therapeutic approach to treat viral
infections. Several studies have demonstrated that increases in the high mutation rates …
infections. Several studies have demonstrated that increases in the high mutation rates …
[HTML][HTML] Recent insights into reverse genetics of norovirus
Q Zhang, S Zhu, X Zhang, L Su, J Ni, Y Zhang, L Fang - Virus Research, 2023 - Elsevier
Norovirus is the leading cause of viral gastroenteritis globally, and poses substantial threats
to public health. Despite substantial progress made in preventing norovirus diseases, the …
to public health. Despite substantial progress made in preventing norovirus diseases, the …
Plasmid-based human norovirus reverse genetics system produces reporter-tagged progeny virus containing infectious genomic RNA
K Katayama, K Murakami, TM Sharp… - Proceedings of the …, 2014 - National Acad Sciences
Human norovirus (HuNoV) is the leading cause of gastroenteritis worldwide. HuNoV
replication studies have been hampered by the inability to grow the virus in cultured cells …
replication studies have been hampered by the inability to grow the virus in cultured cells …
[HTML][HTML] Norovirus translation requires an interaction between the C terminus of the genome-linked viral protein VPg and eukaryotic translation initiation factor 4G
Viruses have evolved a variety of mechanisms to usurp the host cell translation machinery to
enable translation of the viral genome in the presence of high levels of cellular mRNAs …
enable translation of the viral genome in the presence of high levels of cellular mRNAs …
Murine norovirus: additional protocols for basic and antiviral studies
CE Wobus, AM Peiper, AM McSweeney… - Current …, 2023 - Wiley Online Library
Murine norovirus (MNV) is a positive‐sense, plus‐stranded RNA virus in the Caliciviridae
family. Viruses in this family replicate in the intestine and are transmitted by the fecal‐oral …
family. Viruses in this family replicate in the intestine and are transmitted by the fecal‐oral …
[HTML][HTML] Molecular and Genetics-Based Systems for Tracing the Evolution and Exploring the Mechanisms of Human Norovirus Infections
SC Lin, GH Bai, PC Lin, CY Chen, YH Hsu… - International journal of …, 2023 - mdpi.com
Human noroviruses (HuNoV) are major causes of acute gastroenteritis around the world.
The high mutation rate and recombination potential of noroviruses are significant challenges …
The high mutation rate and recombination potential of noroviruses are significant challenges …
[HTML][HTML] Expression of the murine norovirus (MNV) ORF1 polyprotein is sufficient to induce apoptosis in a virus-free cell model
MR Herod, O Salim, RJ Skilton, CA Prince, VK Ward… - PloS one, 2014 - journals.plos.org
Investigations into human norovirus infection, replication and pathogenesis, as well as the
development of potential antiviral agents, have been restricted by the lack of a cell culture …
development of potential antiviral agents, have been restricted by the lack of a cell culture …
[HTML][HTML] Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity
E Emmott, A de Rougemont, M Hosmillo, J Lu… - Journal of Biological …, 2019 - ASBMB
Norovirus infections are a major cause of acute viral gastroenteritis and a significant burden
on global human health. A vital process for norovirus replication is the processing of the …
on global human health. A vital process for norovirus replication is the processing of the …
Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo
Intrahost genetic diversity and replication error rates are intricately linked to RNA virus
pathogenesis, with alterations in viral polymerase fidelity typically leading to attenuation …
pathogenesis, with alterations in viral polymerase fidelity typically leading to attenuation …