Reactive oxygen species drive epigenetic changes in radiation‐induced fibrosis

S Shrishrimal, EA Kosmacek… - … medicine and cellular …, 2019 - Wiley Online Library
Radiation‐induced fibrosis (RIF) develops months to years after initial radiation exposure.
RIF occurs when normal fibroblasts differentiate into myofibroblasts and lay down aberrant …

Radioprotective effects of Carvacrol and/or Thymol against Gamma irradiation-induced acute nephropathy: In silico and in vivo evidence of the involvement of insulin …

YF Mahran, LA Al-Kharashi, RT Atawia, RT Alanazi… - Biomedicines, 2023 - mdpi.com
Radiotherapy (RT) is an effective curative cancer treatment. However, RT can seriously
damage kidney tissues resulting in radiotherapy nephropathy (RN) where oxidative stress …

[HTML][HTML] Protective effects of genistein and melatonin on mouse liver injury induced by whole‑body ionising radiation

G Hanedan Uslu, E Canyilmaz… - Molecular and …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the effectiveness of melatonin and genistein
in preventing radiation therapy (RT)‑induced liver injury in mice. A total of 70 Swiss Albino …

[HTML][HTML] Comparison of the effects of melatonin and genistein on radiation‑induced nephrotoxicity: Results of an experimental study

E Canyilmaz, GH Uslu, Z Bahat… - Biomedical …, 2016 - spandidos-publications.com
The aim of the present study was to compare the effects of melatonin and genistein on
radiation‑induced nephrotoxicity (RIN). A total of 70 Swiss Albino mice were divided into 7 …

Beneficial effects of aminoguanidine on radiotherapy‐induced kidney and testis injury

K Ekici, O Temelli, H Parlakpinar, E Samdanci… - Andrologia, 2016 - Wiley Online Library
This experimental study was designed to investigate both protective and therapeutic effects
of aminoguanidine (AG), on radiotherapy (RT)‐induced oxidative stress in kidney and testis …

The Screening of Renoprotective Agents by 99mTc-DMSA: A Review of Preclinical Studies

M Rezaei, M Papie, M Cheki, L Mansi… - Current …, 2019 - ingentaconnect.com
Background: Nephrotoxicity is a prevalent consequence of cancer treatment using
radiotherapy and chemotherapy or their combination. There are two methods; histological …

[HTML][HTML] Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice

Y Ding, S Liu, M Zhang, M Su… - … Andrology and Urology, 2024 - ncbi.nlm.nih.gov
Background Irradiation (IR) promotes inflammation and apoptosis by inducing oxidative
stress and/or mitochondrial dysfunction (MD). The kidneys are rich in mitochondria, and …

Radioprotective effect of zinc nanoparticles on ionizing radiation-induced nephrotoxicity in mice

I Saadat, M Shakibaie, A Jomehzadeh, A Salimi… - Pharmacology, 2023 - karger.com
Introduction: Ionizing radiation (IR) causes oxidative stress in kidneys and subsequently
disrupts renal function. The use of green synthesized zinc nanoparticles (Zn NPs) with …

Reduction of renal uptake of radiolabeled octreotate by amifostine coadministration

M Melis, R Valkema, EP Krenning… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Megalin-mediated renal retention of radiolabeled somatostatin analogs may lead to
nephrotoxicity during peptide receptor radionuclide therapy (PRRT). The cytoprotective …

[PDF][PDF] Effect of coenzyme Q10 on radiation nephropathy in rats

Y Ki, W Kim, YH Kim, D Kim, JS Bae… - Journal of Korean …, 2017 - synapse.koreamed.org
The kidney is one of the most radiosensitive organs in the abdominal cavity and is the dose-
limiting structure in cancer patients receiving abdominal or total body irradiation. In the …